Vitamin D3 affects mitochondrial biogenesis through mitogen-activated protein kinase in polycystic ovary syndrome mouse model.

Safaei, Zahra; Bakhshalizadeh, Shabnam; Nasr-Esfahani, Mohammad Hossein; Akbari Sene, Azadeh; Najafzadeh, Vahid; Soleimani, Mansoureh; Shirazi, Reza

Safaei, Zahra; Bakhshalizadeh, Shabnam; Nasr-Esfahani, Mohammad Hossein; Akbari Sene, Azadeh; Najafzadeh, Vahid; Soleimani, Mansoureh; Shirazi, Reza.

Safaei Z; Department of Anatomical Sciences, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Bakhshalizadeh S; Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran.
Nasr-Esfahani MH; Department of Anatomical Sciences, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
Akbari Sene A; Department of Cellular Biotechnology, Cell Science Research Center, Royan Institute for Biotechnology, ACECR, Isfahan, Iran.
Najafzadeh V; Department of Obstetrics and Gynecology, Shahid Akbarabadi Hospital IVF Center, Iran University of Medical Sciences, Tehran, Iran.
Soleimani M; Department of Veterinary and Animal Sciences, Anatomy & Biochemistry Section, University of Copenhagen, Copenhagen, Denmark.
Shirazi R; Department of Anatomical Sciences, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

J Cell Physiol ; 235(9): 6113-6126, 2020 09.

Article en En | MEDLINE | ID: mdl-32048305

Asunto(s)

Colecalciferol/farmacología; Sistema de Señalización de MAP Quinasas/efectos de los fármacos; Biogénesis de Organelos; Síndrome del Ovario Poliquístico/tratamiento farmacológico; Animales; Apoptosis/efectos de los fármacos; Catalasa/genética; Deshidroepiandrosterona/toxicidad; Modelos Animales de Enfermedad; Femenino; Glutatión Peroxidasa/genética; Células de la Granulosa/efectos de los fármacos; Humanos; Ratones; Factores Nucleares de Respiración/genética; Coactivador 1-alfa del Receptor Activado por Proliferadores de Peroxisomas gamma/genética; Síndrome del Ovario Poliquístico/inducido químicamente; Síndrome del Ovario Poliquístico/genética; Síndrome del Ovario Poliquístico/patología; Especies Reactivas de Oxígeno/metabolismo; Superóxido Dismutasa/genética

Palabras clave

MAPK-ERK1/2 pathway; granulosa cell; mitochondrial biogenesis; polycystic ovary syndrome; vitamin D3

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Síndrome del Ovario Poliquístico / Biogénesis de Organelos / Colecalciferol / Sistema de Señalización de MAP Quinasas Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Año: 2020 Tipo del documento: Article

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