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Dual Inhibition of Pyruvate Dehydrogenase Complex and Respiratory Chain Complex Induces Apoptosis by a Mitochondria-Targeted Fluorescent Organic Arsenical in vitro and in vivo.
Liu, Yu-Jiao; Fan, Xiao-Yang; Zhang, Dong-Dong; Xia, Yin-Zheng; Hu, Yan-Jun; Jiang, Feng-Lei; Zhou, Fu-Ling; Liu, Yi.
  • Liu YJ; Department of Chemistry, Wuhan University, Wuhan, 430072, China.
  • Fan XY; Department of Chemistry, Wuhan University, Wuhan, 430072, China.
  • Zhang DD; Department of Haematology, Zhongnan Hospital, Wuhan University, Wuhan, 430071, China.
  • Xia YZ; Department of Chemistry, Wuhan University, Wuhan, 430072, China.
  • Hu YJ; College of Chemistry and Materials Science, Nanning Normal University, Nanning, 530001, China.
  • Jiang FL; Department of Chemistry, Wuhan University, Wuhan, 430072, China.
  • Zhou FL; Department of Haematology, Zhongnan Hospital, Wuhan University, Wuhan, 430071, China.
  • Liu Y; Department of Chemistry, Wuhan University, Wuhan, 430072, China.
ChemMedChem ; 15(6): 552-558, 2020 03 18.
Article en En | MEDLINE | ID: mdl-32101363
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Arsenicales / Complejo Piruvato Deshidrogenasa / Leucemia Promielocítica Aguda / Apoptosis / Transporte de Electrón / Inhibidores Enzimáticos / Antineoplásicos Límite: Animals / Female / Humans Idioma: En Año: 2020 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Arsenicales / Complejo Piruvato Deshidrogenasa / Leucemia Promielocítica Aguda / Apoptosis / Transporte de Electrón / Inhibidores Enzimáticos / Antineoplásicos Límite: Animals / Female / Humans Idioma: En Año: 2020 Tipo del documento: Article