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Exogenous GDF11, but not GDF8, reduces body weight and improves glucose homeostasis in mice.
Walker, Ryan G; Barrandon, Ornella; Poggioli, Tommaso; Dagdeviren, Sezin; Carroll, Shannon H; Mills, Melanie J; Mendello, Kourtney R; Gomez, Yanet; Loffredo, Francesco S; Pancoast, James R; Macias-Trevino, Claudio; Marts, Colin; LeClair, Katherine B; Noh, Hye-Lim; Kim, Taekyoon; Banks, Alexander S; Kim, Jason K; Cohen, David E; Wagers, Amy J; Melton, Douglas A; Lee, Richard T.
  • Walker RG; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, 02138, USA.
  • Barrandon O; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, 02138, USA.
  • Poggioli T; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, 02138, USA.
  • Dagdeviren S; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, 02138, USA.
  • Carroll SH; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, 02138, USA.
  • Mills MJ; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, 02138, USA.
  • Mendello KR; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, 02138, USA.
  • Gomez Y; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, 02138, USA.
  • Loffredo FS; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, 02138, USA.
  • Pancoast JR; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, 02138, USA.
  • Macias-Trevino C; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, 02138, USA.
  • Marts C; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, 02138, USA.
  • LeClair KB; Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 02139, USA.
  • Noh HL; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, 01605, USA.
  • Kim T; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, 01605, USA.
  • Banks AS; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
  • Kim JK; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, 01605, USA.
  • Cohen DE; Division of Gastroenterology and Hepatology, Weill Cornell Medicine, New York, NY, USA.
  • Wagers AJ; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, 02138, USA.
  • Melton DA; Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, 02115, USA.
  • Lee RT; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, 02138, USA.
Sci Rep ; 10(1): 4561, 2020 03 12.
Article en En | MEDLINE | ID: mdl-32165710

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Peso Corporal / Envejecimiento / Resistencia a la Insulina / Proteínas Morfogenéticas Óseas / Miostatina / Dieta Alta en Grasa Límite: Animals Idioma: En Año: 2020 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Peso Corporal / Envejecimiento / Resistencia a la Insulina / Proteínas Morfogenéticas Óseas / Miostatina / Dieta Alta en Grasa Límite: Animals Idioma: En Año: 2020 Tipo del documento: Article