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Quinolinecarboxamides Inhibit the Replication of the Bovine Viral Diarrhea Virus by Targeting a Hot Spot for the Inhibition of Pestivirus Replication in the RNA-Dependent RNA Polymerase.
Musiu, Simone; Castillo, Yunierkis Perez; Muigg, Alexandra; Pürstinger, Gerhard; Leyssen, Pieter; Froeyen, Mathy; Neyts, Johan; Paeshuyse, Jan.
  • Musiu S; KU Leuven University, Department of Microbiology and Immunology, Laboratory of Virology and Chemotherapy, Rega Institute for Medical Research, Leuven, Herestraat 49, B-3000 Leuven, Belgium.
  • Castillo YP; Bio-Cheminformatics Research Group and Escuela de Ciencias Físicas y Matemáticas, Universidad de Las Americas, 170150 Quito, Ecuador.
  • Muigg A; Institut für Pharmazie, Abteilung Pharmazeutische Chemie, Universität Innsbruck, Innrain 80/82, A-6020 Innsbruck, Austria.
  • Pürstinger G; Institut für Pharmazie, Abteilung Pharmazeutische Chemie, Universität Innsbruck, Innrain 80/82, A-6020 Innsbruck, Austria.
  • Leyssen P; KU Leuven University, Department of Microbiology and Immunology, Laboratory of Virology and Chemotherapy, Rega Institute for Medical Research, Leuven, Herestraat 49, B-3000 Leuven, Belgium.
  • Froeyen M; KU Leuven University, Department of Pharmaceutical and Pharmacological Sciences, Laboratory of Medicinal Chemistry, Rega Institute for Medical Research, Leuven, Herestraat 49, B-3000 Leuven, Belgium mathy.froeyen@kuleuven.be.
  • Neyts J; KU Leuven University, Department of Microbiology and Immunology, Laboratory of Virology and Chemotherapy, Rega Institute for Medical Research, Leuven, Herestraat 49, B-3000 Leuven, Belgium.
  • Paeshuyse J; KU Leuven, Division Animal and Human Health Engineering, Laboratory for host pathogen interactions, Kasteelpark Arenberg 30, 3001 Leuven, Belgium.
Molecules ; 25(6)2020 Mar 12.
Article en En | MEDLINE | ID: mdl-32178258

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Replicación Viral / Diarrea Mucosa Bovina Viral / Pestivirus / Virus de la Diarrea Viral Bovina Límite: Animals Idioma: En Año: 2020 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Replicación Viral / Diarrea Mucosa Bovina Viral / Pestivirus / Virus de la Diarrea Viral Bovina Límite: Animals Idioma: En Año: 2020 Tipo del documento: Article