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Activation of notch 3/c-MYC/CHOP axis regulates apoptosis and promotes sensitivity of lung cancer cells to mTOR inhibitor everolimus.
Li, Ting; Xu, Xiao-Huang; Guo, Xia; Yuan, Tao; Tang, Zheng-Hai; Jiang, Xiao-Ming; Xu, Yu-Lian; Zhang, Le-Le; Chen, Xiuping; Zhu, Hong; Shi, Jia-Jie; Lu, Jin-Jian.
  • Li T; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
  • Xu XH; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
  • Guo X; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
  • Yuan T; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
  • Tang ZH; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
  • Jiang XM; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
  • Xu YL; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
  • Zhang LL; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
  • Chen X; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
  • Zhu H; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
  • Shi JJ; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
  • Lu JJ; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China. Electronic address: jinjianlu@um.edu.mo.
Biochem Pharmacol ; 175: 113921, 2020 05.
Article en En | MEDLINE | ID: mdl-32201213
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Factores de Transcripción / Proteínas de Unión al ADN / Factor de Transcripción CHOP / Serina-Treonina Quinasas TOR / Everolimus / Receptor Notch3 / Neoplasias Pulmonares Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Factores de Transcripción / Proteínas de Unión al ADN / Factor de Transcripción CHOP / Serina-Treonina Quinasas TOR / Everolimus / Receptor Notch3 / Neoplasias Pulmonares Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article