Iron deficiency-induced loss of skeletal muscle mitochondrial proteins and respiratory capacity; the role of mitophagy and secretion of mitochondria-containing vesicles.

Leermakers, Pieter A; Remels, Alexander H V; Zonneveld, Marijke I; Rouschop, Kasper M A; Schols, Annemie M W J; Gosker, Harry R

Leermakers, Pieter A; Remels, Alexander H V; Zonneveld, Marijke I; Rouschop, Kasper M A; Schols, Annemie M W J; Gosker, Harry R.

Leermakers PA; Department of Respiratory Medicine, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, Maastricht, the Netherlands.
Remels AHV; Department of Pharmacology and Toxicology, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, Maastricht, the Netherlands.
Zonneveld MI; Department of Radiotherapy, GROW School for Oncology and Developmental Biology, Maastricht University Medical Centre+, Maastricht, the Netherlands.
Rouschop KMA; Department of Radiotherapy, GROW School for Oncology and Developmental Biology, Maastricht University Medical Centre+, Maastricht, the Netherlands.
Schols AMWJ; Department of Respiratory Medicine, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, Maastricht, the Netherlands.
Gosker HR; Department of Respiratory Medicine, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, Maastricht, the Netherlands.

FASEB J ; 34(5): 6703-6717, 2020 05.

Article en En | MEDLINE | ID: mdl-32202346

Asunto(s)

Deficiencias de Hierro; Mitocondrias Musculares/patología; Mitocondrias/patología; Proteínas Mitocondriales/metabolismo; Mitofagia; Músculo Esquelético/patología; Vesículas Secretoras/metabolismo; Animales; Proteínas de la Membrana/genética; Proteínas de la Membrana/metabolismo; Ratones; Mitocondrias/metabolismo; Mitocondrias Musculares/metabolismo; Proteínas Mitocondriales/genética; Músculo Esquelético/metabolismo; Especies Reactivas de Oxígeno

Palabras clave

extracellular vesicles; iron depletion; mitochondrial clearance; myotubes

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Músculo Esquelético / Vesículas Secretoras / Proteínas Mitocondriales / Mitofagia / Deficiencias de Hierro / Mitocondrias / Mitocondrias Musculares Límite: Animals Idioma: En Año: 2020 Tipo del documento: Article

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