Genetic Architecture of Gene Expression in European and African Americans: An eQTL Mapping Study in GENOA.

Shang, Lulu; Smith, Jennifer A; Zhao, Wei; Kho, Minjung; Turner, Stephen T; Mosley, Thomas H; Kardia, Sharon L R; Zhou, Xiang

Shang, Lulu; Smith, Jennifer A; Zhao, Wei; Kho, Minjung; Turner, Stephen T; Mosley, Thomas H; Kardia, Sharon L R; Zhou, Xiang.

Shang L; Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI 48109, USA.
Smith JA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109, USA.
Zhao W; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109, USA.
Kho M; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109, USA.
Turner ST; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN 55905, USA.
Mosley TH; Memory Impairment and Neurodegenerative Dementia (MIND) Center, University of Mississippi Medical Center, Jackson, MS 39126, USA.
Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: skardia@umich.edu.
Zhou X; Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: xzhousph@umich.edu.

Am J Hum Genet ; 106(4): 496-512, 2020 04 02.

Article en En | MEDLINE | ID: mdl-32220292

Asunto(s)

Negro o Afroamericano/genética; Regulación de la Expresión Génica/genética; Sitios de Carácter Cuantitativo/genética; Población Blanca/genética; Mapeo Cromosómico/métodos; Estudios de Cohortes; Femenino; Predisposición Genética a la Enfermedad/genética; Estudio de Asociación del Genoma Completo/métodos; Humanos; Masculino; Polimorfismo de Nucleótido Simple/genética; Transcriptoma/genética

Palabras clave

African American; European American; GENOA; eGenes; eQTLs; eSNPs; gene expression; lymphoblastoid cell lines; quantitative trait loci

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Negro o Afroamericano / Regulación de la Expresión Génica / Sitios de Carácter Cuantitativo / Población Blanca Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Male Idioma: En Año: 2020 Tipo del documento: Article

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