Improved two-stage estimation to adjust for treatment switching in randomised trials: g-estimation to address time-dependent confounding.

Latimer, N R; White, I R; Tilling, K; Siebert, U

Latimer, N R; White, I R; Tilling, K; Siebert, U.

Latimer NR; School of Health and Related Research, University of Sheffield, Sheffield, UK.
White IR; MRC Clinical Trials Unit, University College London, London, UK.
Tilling K; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Siebert U; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.

Stat Methods Med Res ; 29(10): 2900-2918, 2020 10.

Article en En | MEDLINE | ID: mdl-32223524

Asunto(s)

Neoplasias; Cambio de Tratamiento; Humanos; Probabilidad; Tamaño de la Muestra; Análisis de Supervivencia

Palabras clave

Treatment switching; counterfactual; g-estimation; health technology assessment; oncology; overall survival; prediction; structural nested models; survival analysis; time-dependent confounding; time-to-event outcomes; treatment crossover

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cambio de Tratamiento / Neoplasias Tipo de estudio: Clinical_trials / Health_technology_assessment / Prognostic_studies Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article

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