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Notch1-mediated histone demethylation of HCN4 contributes to aconitine-induced ventricular myocardial dysrhythmia.
Zhou, Wei; Qiu, Li-Zhen; Liu, Hong; Deng, Hui-Fang; Yue, Lan-Xin; Gao, Yue.
  • Zhou W; Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing, 100850, PR China.
  • Qiu LZ; Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, PR China.
  • Liu H; School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, 510006, PR China.
  • Deng HF; Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing, 100850, PR China.
  • Yue LX; Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing, 100850, PR China.
  • Gao Y; Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing, 100850, PR China; Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, PR China. Electronic address: gaoyue@bmi.ac.cn.
Toxicol Lett ; 327: 19-31, 2020 Jul 01.
Article en En | MEDLINE | ID: mdl-32234357
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Arritmias Cardíacas / Aconitina / Canales de Potasio / Receptor Notch1 / Canales Regulados por Nucleótidos Cíclicos Activados por Hiperpolarización / Ventrículos Cardíacos Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2020 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Arritmias Cardíacas / Aconitina / Canales de Potasio / Receptor Notch1 / Canales Regulados por Nucleótidos Cíclicos Activados por Hiperpolarización / Ventrículos Cardíacos Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2020 Tipo del documento: Article