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Neoadjuvant immunotherapy leads to pathological responses in MMR-proficient and MMR-deficient early-stage colon cancers.
Chalabi, Myriam; Fanchi, Lorenzo F; Dijkstra, Krijn K; Van den Berg, José G; Aalbers, Arend G; Sikorska, Karolina; Lopez-Yurda, Marta; Grootscholten, Cecile; Beets, Geerard L; Snaebjornsson, Petur; Maas, Monique; Mertz, Marjolijn; Veninga, Vivien; Bounova, Gergana; Broeks, Annegien; Beets-Tan, Regina G; de Wijkerslooth, Thomas R; van Lent, Anja U; Marsman, Hendrik A; Nuijten, Elvira; Kok, Niels F; Kuiper, Maria; Verbeek, Wieke H; Kok, Marleen; Van Leerdam, Monique E; Schumacher, Ton N; Voest, Emile E; Haanen, John B.
  • Chalabi M; Gastrointestinal Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands. m.chalabi@nki.nl.
  • Fanchi LF; Molecular Oncology and Immunology, Netherlands Cancer Institute, Amsterdam, the Netherlands. m.chalabi@nki.nl.
  • Dijkstra KK; Medical Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands. m.chalabi@nki.nl.
  • Van den Berg JG; Molecular Oncology and Immunology, Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Aalbers AG; Oncode Institute, Utrecht, the Netherlands.
  • Sikorska K; Molecular Oncology and Immunology, Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Lopez-Yurda M; Oncode Institute, Utrecht, the Netherlands.
  • Grootscholten C; Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Beets GL; Surgical Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Snaebjornsson P; Biometrics, Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Maas M; Biometrics, Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Mertz M; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.
  • Veninga V; Gastrointestinal Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Bounova G; Surgical Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Broeks A; GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, the Netherlands.
  • Beets-Tan RG; Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • de Wijkerslooth TR; Radiology, Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • van Lent AU; Bioimaging Facility, Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Marsman HA; Molecular Oncology and Immunology, Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Nuijten E; Oncode Institute, Utrecht, the Netherlands.
  • Kok NF; Oncode Institute, Utrecht, the Netherlands.
  • Kuiper M; Molecular Carcinogenesis, Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Verbeek WH; Core Facility Molecular Pathology & Biobanking, Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Kok M; GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, the Netherlands.
  • Van Leerdam ME; Radiology, Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Schumacher TN; Gastrointestinal Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Voest EE; Gastroenterology & Hepatology, Onze Lieve Vrouwe Gasthuis, Amsterdam, the Netherlands.
  • Haanen JB; Surgery, Onze Lieve Vrouwe Gasthuis, Amsterdam, the Netherlands.
Nat Med ; 26(4): 566-576, 2020 04.
Article en En | MEDLINE | ID: mdl-32251400

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Adenocarcinoma / Neoplasias del Colon / Reparación de la Incompatibilidad de ADN / Antineoplásicos Inmunológicos / Inmunoterapia Tipo de estudio: Clinical_trials Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Año: 2020 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Adenocarcinoma / Neoplasias del Colon / Reparación de la Incompatibilidad de ADN / Antineoplásicos Inmunológicos / Inmunoterapia Tipo de estudio: Clinical_trials Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Año: 2020 Tipo del documento: Article