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The miR-185/PAK6 axis predicts therapy response and regulates survival of drug-resistant leukemic stem cells in CML.
Lin, Hanyang; Rothe, Katharina; Chen, Min; Wu, Andrew; Babaian, Artem; Yen, Ryan; Zeng, Jonathan; Ruschmann, Jens; Petriv, Oleh I; O'Neill, Kieran; Maetzig, Tobias; Knapp, David J H F; Nakamichi, Naoto; Brinkman, Ryan; Birol, Inanc; Forrest, Donna L; Hansen, Carl; Humphries, R Keith; Eaves, Connie J; Jiang, Xiaoyan.
  • Lin H; Terry Fox Laboratory, British Columbia Cancer Research Institute, Vancouver, BC, Canada.
  • Rothe K; Department of Medicine.
  • Chen M; Terry Fox Laboratory, British Columbia Cancer Research Institute, Vancouver, BC, Canada.
  • Wu A; Department of Medical Genetics.
  • Babaian A; Terry Fox Laboratory, British Columbia Cancer Research Institute, Vancouver, BC, Canada.
  • Yen R; Terry Fox Laboratory, British Columbia Cancer Research Institute, Vancouver, BC, Canada.
  • Zeng J; Department of Medicine.
  • Ruschmann J; Terry Fox Laboratory, British Columbia Cancer Research Institute, Vancouver, BC, Canada.
  • Petriv OI; Department of Medical Genetics.
  • O'Neill K; Terry Fox Laboratory, British Columbia Cancer Research Institute, Vancouver, BC, Canada.
  • Maetzig T; Department of Medicine.
  • Knapp DJHF; Terry Fox Laboratory, British Columbia Cancer Research Institute, Vancouver, BC, Canada.
  • Nakamichi N; Terry Fox Laboratory, British Columbia Cancer Research Institute, Vancouver, BC, Canada.
  • Brinkman R; Center for High-Throughput Biology, and.
  • Birol I; Department of Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada.
  • Forrest DL; Terry Fox Laboratory, British Columbia Cancer Research Institute, Vancouver, BC, Canada.
  • Hansen C; Terry Fox Laboratory, British Columbia Cancer Research Institute, Vancouver, BC, Canada.
  • Humphries RK; Terry Fox Laboratory, British Columbia Cancer Research Institute, Vancouver, BC, Canada.
  • Eaves CJ; Department of Medicine.
  • Jiang X; Terry Fox Laboratory, British Columbia Cancer Research Institute, Vancouver, BC, Canada.
Blood ; 136(5): 596-609, 2020 07 30.
Article en En | MEDLINE | ID: mdl-32270193
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Células Madre Neoplásicas / Leucemia Mielógena Crónica BCR-ABL Positiva / Resistencia a Antineoplásicos / MicroARNs / Quinasas p21 Activadas Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Células Madre Neoplásicas / Leucemia Mielógena Crónica BCR-ABL Positiva / Resistencia a Antineoplásicos / MicroARNs / Quinasas p21 Activadas Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Año: 2020 Tipo del documento: Article