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Hepatocellular Carcinoma Cells Up-regulate PVRL1, Stabilizing PVR and Inhibiting the Cytotoxic T-Cell Response via TIGIT to Mediate Tumor Resistance to PD1 Inhibitors in Mice.
Chiu, David Kung-Chun; Yuen, Vincent Wai-Hin; Cheu, Jacinth Wing-Sum; Wei, Larry Lai; Ting, Vox; Fehlings, Michael; Sumatoh, Hermi; Nardin, Alessandra; Newell, Evan W; Ng, Irene Oi-Lin; Yau, Thomas Chung-Cheung; Wong, Chun-Ming; Wong, Carmen Chak-Lui.
  • Chiu DK; Department of Pathology, The University of Hong Kong, Hong Kong.
  • Yuen VW; Department of Pathology, The University of Hong Kong, Hong Kong.
  • Cheu JW; Department of Pathology, The University of Hong Kong, Hong Kong.
  • Wei LL; Department of Pathology, The University of Hong Kong, Hong Kong.
  • Ting V; Department of Medicine, The University of Hong Kong, Hong Kong.
  • Fehlings M; ImmunoSCAPE Pte Ltd, Singapore.
  • Sumatoh H; ImmunoSCAPE Pte Ltd, Singapore.
  • Nardin A; ImmunoSCAPE Pte Ltd, Singapore.
  • Newell EW; ImmunoSCAPE Pte Ltd, Singapore; Vaccine and Infections Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
  • Ng IO; Department of Pathology, The University of Hong Kong, Hong Kong; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong.
  • Yau TC; Department of Medicine, The University of Hong Kong, Hong Kong; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong.
  • Wong CM; Department of Pathology, The University of Hong Kong, Hong Kong; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong.
  • Wong CC; Department of Pathology, The University of Hong Kong, Hong Kong; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong. Electronic address: carmencl@pathology.hku.hk.
Gastroenterology ; 159(2): 609-623, 2020 08.
Article en En | MEDLINE | ID: mdl-32275969
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Carcinoma Hepatocelular / Resistencia a Antineoplásicos / Nectinas / Inhibidores de Puntos de Control Inmunológico / Neoplasias Hepáticas Tipo de estudio: Prognostic_studies Idioma: En Año: 2020 Tipo del documento: Article
Texto completo
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XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Carcinoma Hepatocelular / Resistencia a Antineoplásicos / Nectinas / Inhibidores de Puntos de Control Inmunológico / Neoplasias Hepáticas Tipo de estudio: Prognostic_studies Idioma: En Año: 2020 Tipo del documento: Article