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A database for inventory of proteoform profiles: "2DE-pattern".
Naryzhny, Stanislav; Klopov, Nikolay; Ronzhina, Natalia; Zorina, Elena; Zgoda, Victor; Kleyst, Olga; Belyakova, Natalia; Legina, Olga.
  • Naryzhny S; Orekhovich Institute of Biomedical Chemistry of Russian Academy of Medical Sciences, Moscow, Russia.
  • Klopov N; B.P. Konstantinov Petersburg Nuclear Physics Institute, National Research Center "Kurchatov Institute", Gatchina, Russia.
  • Ronzhina N; B.P. Konstantinov Petersburg Nuclear Physics Institute, National Research Center "Kurchatov Institute", Gatchina, Russia.
  • Zorina E; B.P. Konstantinov Petersburg Nuclear Physics Institute, National Research Center "Kurchatov Institute", Gatchina, Russia.
  • Zgoda V; Orekhovich Institute of Biomedical Chemistry of Russian Academy of Medical Sciences, Moscow, Russia.
  • Kleyst O; Orekhovich Institute of Biomedical Chemistry of Russian Academy of Medical Sciences, Moscow, Russia.
  • Belyakova N; B.P. Konstantinov Petersburg Nuclear Physics Institute, National Research Center "Kurchatov Institute", Gatchina, Russia.
  • Legina O; B.P. Konstantinov Petersburg Nuclear Physics Institute, National Research Center "Kurchatov Institute", Gatchina, Russia.
Electrophoresis ; 41(12): 1118-1124, 2020 06.
Article en En | MEDLINE | ID: mdl-32307725
ABSTRACT
The human proteome is composed of a diverse and heterogeneous range of gene products/proteoforms/protein species. Because of the growing amount of information about proteoforms generated by different methods, we need a convenient approach to make an inventory of the data. Here, we present a database of proteoforms that is based on information obtained by separation of proteoforms using 2DE followed by shotgun ESI-LC-MS/MS. The database's principles and structure are described. The database is called "2DE-pattern" as it contains multiple isoform-centric patterns of proteoforms separated according to 2DE principles. The database can be freely used at http//2de-pattern.pnpi.nrcki.ru.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Electroforesis en Gel Bidimensional / Isoformas de Proteínas / Proteoma / Bases de Datos de Proteínas Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Electroforesis en Gel Bidimensional / Isoformas de Proteínas / Proteoma / Bases de Datos de Proteínas Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article