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The NSD2 p.E1099K Mutation Is Enriched at Relapse and Confers Drug Resistance in a Cell Context-Dependent Manner in Pediatric Acute Lymphoblastic Leukemia.
Pierro, Joanna; Saliba, Jason; Narang, Sonali; Sethia, Gunjan; Saint Fleur-Lominy, Shella; Chowdhury, Ashfiyah; Qualls, Anita; Fay, Hannah; Kilberg, Harrison L; Moriyama, Takaya; Fuller, Tori J; Teachey, David T; Schmiegelow, Kjeld; Yang, Jun J; Loh, Mignon L; Brown, Patrick A; Zhang, Jinghui; Ma, Xiaotu; Tsirigos, Aristotelis; Evensen, Nikki A; Carroll, William L.
  • Pierro J; Departments of Pediatrics and Pathology, Perlmutter Cancer Center, NYU Langone Health, New York, New York.
  • Saliba J; Division of Pediatric Hematology/Oncology, Hassenfeld Children's Hospital at NYU Langone Health, New York, New York.
  • Narang S; Departments of Pediatrics and Pathology, Perlmutter Cancer Center, NYU Langone Health, New York, New York.
  • Sethia G; Departments of Pediatrics and Pathology, Perlmutter Cancer Center, NYU Langone Health, New York, New York.
  • Saint Fleur-Lominy S; Departments of Pediatrics and Pathology, Perlmutter Cancer Center, NYU Langone Health, New York, New York.
  • Chowdhury A; Departments of Pediatrics and Pathology, Perlmutter Cancer Center, NYU Langone Health, New York, New York.
  • Qualls A; Division of Medical Hematology/Oncology, NYU Langone Health, New York, New York.
  • Fay H; Departments of Pediatrics and Pathology, Perlmutter Cancer Center, NYU Langone Health, New York, New York.
  • Kilberg HL; Departments of Pediatrics and Pathology, Perlmutter Cancer Center, NYU Langone Health, New York, New York.
  • Moriyama T; Departments of Pediatrics and Pathology, Perlmutter Cancer Center, NYU Langone Health, New York, New York.
  • Fuller TJ; Departments of Pediatrics and Pathology, Perlmutter Cancer Center, NYU Langone Health, New York, New York.
  • Teachey DT; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee.
  • Schmiegelow K; Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia and The Perelman School of Medicine at The University of Pennsylvania, Philadelphia, Pennsylvania.
  • Yang JJ; Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia and The Perelman School of Medicine at The University of Pennsylvania, Philadelphia, Pennsylvania.
  • Loh ML; Department of Pediatrics and Adolescent Medicine, The University Hospital Rigshospitalet, Copenhagen, Denmark.
  • Brown PA; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee.
  • Zhang J; Department of Pediatrics, Benioff Children's Hospital and The Helen Diller Family Comprehensive Cancer Center University of California, San Francisco, San Francisco, California.
  • Ma X; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins University School of Medicine, Baltimore, Maryland.
  • Tsirigos A; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee.
  • Evensen NA; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee.
  • Carroll WL; Departments of Pediatrics and Pathology, Perlmutter Cancer Center, NYU Langone Health, New York, New York.
Mol Cancer Res ; 18(8): 1153-1165, 2020 08.
Article en En | MEDLINE | ID: mdl-32332049
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Represoras / N-Metiltransferasa de Histona-Lisina / Resistencia a Antineoplásicos / Perfilación de la Expresión Génica / Leucemia-Linfoma Linfoblástico de Células Precursoras / Mutación / Recurrencia Local de Neoplasia Tipo de estudio: Prognostic_studies Límite: Animals / Child / Humans Idioma: En Año: 2020 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Represoras / N-Metiltransferasa de Histona-Lisina / Resistencia a Antineoplásicos / Perfilación de la Expresión Génica / Leucemia-Linfoma Linfoblástico de Células Precursoras / Mutación / Recurrencia Local de Neoplasia Tipo de estudio: Prognostic_studies Límite: Animals / Child / Humans Idioma: En Año: 2020 Tipo del documento: Article