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A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.
Gordon, David E; Jang, Gwendolyn M; Bouhaddou, Mehdi; Xu, Jiewei; Obernier, Kirsten; White, Kris M; O'Meara, Matthew J; Rezelj, Veronica V; Guo, Jeffrey Z; Swaney, Danielle L; Tummino, Tia A; Hüttenhain, Ruth; Kaake, Robyn M; Richards, Alicia L; Tutuncuoglu, Beril; Foussard, Helene; Batra, Jyoti; Haas, Kelsey; Modak, Maya; Kim, Minkyu; Haas, Paige; Polacco, Benjamin J; Braberg, Hannes; Fabius, Jacqueline M; Eckhardt, Manon; Soucheray, Margaret; Bennett, Melanie J; Cakir, Merve; McGregor, Michael J; Li, Qiongyu; Meyer, Bjoern; Roesch, Ferdinand; Vallet, Thomas; Mac Kain, Alice; Miorin, Lisa; Moreno, Elena; Naing, Zun Zar Chi; Zhou, Yuan; Peng, Shiming; Shi, Ying; Zhang, Ziyang; Shen, Wenqi; Kirby, Ilsa T; Melnyk, James E; Chorba, John S; Lou, Kevin; Dai, Shizhong A; Barrio-Hernandez, Inigo; Memon, Danish; Hernandez-Armenta, Claudia.
  • Gordon DE; QBI COVID-19 Research Group (QCRG), San Francisco, CA, USA.
  • Jang GM; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, USA.
  • Bouhaddou M; J. David Gladstone Institutes, San Francisco, CA, USA.
  • Xu J; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, USA.
  • Obernier K; QBI COVID-19 Research Group (QCRG), San Francisco, CA, USA.
  • White KM; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, USA.
  • O'Meara MJ; J. David Gladstone Institutes, San Francisco, CA, USA.
  • Rezelj VV; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, USA.
  • Guo JZ; QBI COVID-19 Research Group (QCRG), San Francisco, CA, USA.
  • Swaney DL; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, USA.
  • Tummino TA; J. David Gladstone Institutes, San Francisco, CA, USA.
  • Hüttenhain R; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, USA.
  • Kaake RM; QBI COVID-19 Research Group (QCRG), San Francisco, CA, USA.
  • Richards AL; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, USA.
  • Tutuncuoglu B; J. David Gladstone Institutes, San Francisco, CA, USA.
  • Foussard H; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, USA.
  • Batra J; QBI COVID-19 Research Group (QCRG), San Francisco, CA, USA.
  • Haas K; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, USA.
  • Modak M; J. David Gladstone Institutes, San Francisco, CA, USA.
  • Kim M; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, USA.
  • Haas P; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Polacco BJ; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Braberg H; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
  • Fabius JM; Viral Populations and Pathogenesis Unit, CNRS UMR 3569, Institut Pasteur, Paris, France.
  • Eckhardt M; QBI COVID-19 Research Group (QCRG), San Francisco, CA, USA.
  • Soucheray M; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, USA.
  • Bennett MJ; J. David Gladstone Institutes, San Francisco, CA, USA.
  • Cakir M; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, USA.
  • McGregor MJ; QBI COVID-19 Research Group (QCRG), San Francisco, CA, USA.
  • Li Q; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, USA.
  • Meyer B; J. David Gladstone Institutes, San Francisco, CA, USA.
  • Roesch F; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, USA.
  • Vallet T; QBI COVID-19 Research Group (QCRG), San Francisco, CA, USA.
  • Mac Kain A; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, USA.
  • Miorin L; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, USA.
  • Moreno E; QBI COVID-19 Research Group (QCRG), San Francisco, CA, USA.
  • Naing ZZC; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, USA.
  • Zhou Y; J. David Gladstone Institutes, San Francisco, CA, USA.
  • Peng S; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, USA.
  • Shi Y; QBI COVID-19 Research Group (QCRG), San Francisco, CA, USA.
  • Zhang Z; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, USA.
  • Shen W; J. David Gladstone Institutes, San Francisco, CA, USA.
  • Kirby IT; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, USA.
  • Melnyk JE; QBI COVID-19 Research Group (QCRG), San Francisco, CA, USA.
  • Chorba JS; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, USA.
  • Lou K; J. David Gladstone Institutes, San Francisco, CA, USA.
  • Dai SA; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, USA.
  • Barrio-Hernandez I; QBI COVID-19 Research Group (QCRG), San Francisco, CA, USA.
  • Memon D; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, USA.
  • Hernandez-Armenta C; J. David Gladstone Institutes, San Francisco, CA, USA.
Nature ; 583(7816): 459-468, 2020 07.
Article en En | MEDLINE | ID: mdl-32353859
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neumonía Viral / Proteínas Virales / Infecciones por Coronavirus / Reposicionamiento de Medicamentos / Terapia Molecular Dirigida / Mapas de Interacción de Proteínas / Betacoronavirus Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2020 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neumonía Viral / Proteínas Virales / Infecciones por Coronavirus / Reposicionamiento de Medicamentos / Terapia Molecular Dirigida / Mapas de Interacción de Proteínas / Betacoronavirus Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2020 Tipo del documento: Article