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SnapShot: Lysosomal Functions.
Holland, Lya K K; Nielsen, Inger Ødum; Maeda, Kenji; Jäättelä, Marja.
  • Holland LKK; Cell Death and Metabolism Unit, Center for Autophagy, Recycling and Disease, Danish Cancer Society Research Center, DK-2100 Copenhagen, Denmark.
  • Nielsen IØ; Cell Death and Metabolism Unit, Center for Autophagy, Recycling and Disease, Danish Cancer Society Research Center, DK-2100 Copenhagen, Denmark.
  • Maeda K; Cell Death and Metabolism Unit, Center for Autophagy, Recycling and Disease, Danish Cancer Society Research Center, DK-2100 Copenhagen, Denmark.
  • Jäättelä M; Cell Death and Metabolism Unit, Center for Autophagy, Recycling and Disease, Danish Cancer Society Research Center, DK-2100 Copenhagen, Denmark; Department of Cellular and Molecular Medicine, University of Copenhagen, DK-2200 Copenhagen, Denmark.
Cell ; 181(3): 748-748.e1, 2020 04 30.
Article en En | MEDLINE | ID: mdl-32359442
In addition to their well-defined recycling function, lysosomes act as metabolic signaling hubs that adjust cellular metabolism according to the availability of nutrients and growth factors by regulating metabolic kinases and transcription factors on their surface. Moreover, lysosomal hydrolases and ions released to cytosol or extracellular space have recently emerged as important regulators of various cellular processes from cell death to cell division. To view this SnapShot, open or download the PDF.
Asunto(s)

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Lisosomas Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Lisosomas Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article