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ALS/FTD-associated protein FUS induces mitochondrial dysfunction by preferentially sequestering respiratory chain complex mRNAs.
Tsai, Yueh-Lin; Coady, Tristan H; Lu, Lei; Zheng, Dinghai; Alland, Isabel; Tian, Bin; Shneider, Neil A; Manley, James L.
  • Tsai YL; Department of Biological Sciences, Columbia University, New York, New York 10027, USA.
  • Coady TH; Department of Biological Sciences, Columbia University, New York, New York 10027, USA.
  • Lu L; Center for Motor Neuron Biology and Disease, Columbia University, New York, New York 10027, USA.
  • Zheng D; Department of Microbiology, Biochemistry, and Molecular Genetics, Rutgers New Jersey Medical School, Newark, New Jersey 07103, USA.
  • Alland I; Department of Biological Sciences, Columbia University, New York, New York 10027, USA.
  • Tian B; Department of Microbiology, Biochemistry, and Molecular Genetics, Rutgers New Jersey Medical School, Newark, New Jersey 07103, USA.
  • Shneider NA; Center for Motor Neuron Biology and Disease, Columbia University, New York, New York 10027, USA.
  • Manley JL; Department of Biological Sciences, Columbia University, New York, New York 10027, USA.
Genes Dev ; 34(11-12): 785-805, 2020 06 01.
Article en En | MEDLINE | ID: mdl-32381627
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: ARN Mensajero / Regulación de la Expresión Génica / Proteína FUS de Unión a ARN / Esclerosis Amiotrófica Lateral / Mitocondrias Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: ARN Mensajero / Regulación de la Expresión Génica / Proteína FUS de Unión a ARN / Esclerosis Amiotrófica Lateral / Mitocondrias Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article