ACQ-to-AIE Transformation: Tuning Molecular Packing by Regioisomerization for Two-Photon NIR Bioimaging.
Angew Chem Int Ed Engl
; 59(31): 12822-12826, 2020 07 27.
Article
en En
| MEDLINE
| ID: mdl-32385974
ABSTRACT
The traditional design strategies for highly bright solid-state luminescent materials rely on weakening the intermolecular π-π interactions, which may limit diversity when developing new materials. Herein, we propose a strategy of tuning the molecular packing mode by regioisomerization to regulate the solid-state fluorescence. TBP-e-TPA with a molecular rotor in the end position of a planar core adopts a long-range cofacial packing mode, which in the solid state is almost non-emissive. By shifting molecular rotors to the bay position, the resultant TBP-b-TPA possesses a discrete cross packing mode, giving a quantum yield of 15.6±0.2 %. These results demonstrate the relationship between the solid-state fluorescence efficiency and the molecule's packing mode. Thanks to the good photophysical properties, TBP-b-TPA nanoparticles were used for two-photon deep brain imaging. This molecular design philosophy provides a new way of designing highly bright solid-state fluorophores.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Fenazinas
/
Tiofenos
/
Colorantes Fluorescentes
/
Compuestos de Anilina
Límite:
Animals
/
Humans
Idioma:
En
Año:
2020
Tipo del documento:
Article