Optimizing neuromelanin contrast in the substantia nigra and locus coeruleus using a magnetization transfer contrast prepared 3D gradient recalled echo sequence.

Liu, Yu; Li, Junchen; He, Naying; Chen, Yongsheng; Jin, Zhijia; Yan, Fuhua; Haacke, E Mark

Liu, Yu; Li, Junchen; He, Naying; Chen, Yongsheng; Jin, Zhijia; Yan, Fuhua; Haacke, E Mark.

Liu Y; Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai, 200025, China.
Li J; Department of Radiology, Changshu Hospital Affiliated to Nanjing University of Chinese Medicine, No. 6 Huanghe Road, Changshu, 215500, China.
He N; Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai, 200025, China.
Chen Y; Department of Neurology, Wayne State University, 4201 St. Antoine, Detroit, MI, 48201, USA. Electronic address: ys.chen@wayne.edu.
Jin Z; Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai, 200025, China.
Yan F; Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai, 200025, China. Electronic address: yfh11655@rjh.com.cn.
Haacke EM; Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai, 200025, China; Department of Neurology, Wayne State University, 4201 St. Antoine, Detroit, MI, 48201, USA; Department of Biomedical Engineering, Wayne State University, 3990

Neuroimage ; 218: 116935, 2020 09.

Article en En | MEDLINE | ID: mdl-32413460

Asunto(s)

Imagenología Tridimensional/métodos; Locus Coeruleus/diagnóstico por imagen; Imagen por Resonancia Magnética/métodos; Melaninas/metabolismo; Sustancia Negra/diagnóstico por imagen; Adulto; Artefactos; Biomarcadores; Agua Corporal; Simulación por Computador; Imagen Eco-Planar; Femenino; Humanos; Locus Coeruleus/metabolismo; Masculino; Sustancia Negra/metabolismo; Adulto Joven

Palabras clave

Magnetization transfer contrast; Neuromelanin; Parkinson's disease; Quantitative MRI; STAGE imaging

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Locus Coeruleus / Sustancia Negra / Imagen por Resonancia Magnética / Imagenología Tridimensional / Melaninas Límite: Adult / Female / Humans / Male Idioma: En Año: 2020 Tipo del documento: Article

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