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Insights into the degradation chemistry of tazarotene, a third generation acetylenic retinoid: LC-HRMS (Orbitrap), LC-MSn and NMR characterization of its degradation products, and prediction of their physicochemical and ADMET properties.
Singh, Dilip Kumar; Sahu, Archana; Balhara, Ankit; Giri, Sanjeev; Singh, Saranjit.
  • Singh DK; Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S. A. S. Nagar 160 062, Punjab, India.
  • Sahu A; Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S. A. S. Nagar 160 062, Punjab, India.
  • Balhara A; Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S. A. S. Nagar 160 062, Punjab, India.
  • Giri S; DMPK and Pharmaceutical Development, Aurigene Discovery Technologies Limited, Hyderabad, 500 049, Telangana, India.
  • Singh S; Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S. A. S. Nagar 160 062, Punjab, India. Electronic address: ssingh@niper.ac.in.
J Pharm Biomed Anal ; 186: 113316, 2020 Jul 15.
Article en En | MEDLINE | ID: mdl-32413825
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cromatografía Liquida / Fármacos Dermatológicos / Ácidos Nicotínicos Idioma: En Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cromatografía Liquida / Fármacos Dermatológicos / Ácidos Nicotínicos Idioma: En Año: 2020 Tipo del documento: Article