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Exploration of carbamide derived pyrimidine-thioindole conjugates as potential VEGFR-2 inhibitors with anti-angiogenesis effect.
Sana, Sravani; Reddy, Velma Ganga; Bhandari, Sonal; Reddy, T Srinivasa; Tokala, Ramya; Sakla, Akash P; Bhargava, Suresh K; Shankaraiah, Nagula.
  • Sana S; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, 500 037, India.
  • Reddy VG; Centre for Advanced Materials & Industrial Chemistry (CAMIC), School of Science, RMIT University, GPO Box 2476, Melbourne, 3001, Australia. Electronic address: ganga.reddy.velma@rmit.edu.au.
  • Bhandari S; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, 500 037, India.
  • Reddy TS; Centre for Advanced Materials & Industrial Chemistry (CAMIC), School of Science, RMIT University, GPO Box 2476, Melbourne, 3001, Australia.
  • Tokala R; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, 500 037, India.
  • Sakla AP; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, 500 037, India.
  • Bhargava SK; Centre for Advanced Materials & Industrial Chemistry (CAMIC), School of Science, RMIT University, GPO Box 2476, Melbourne, 3001, Australia.
  • Shankaraiah N; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, 500 037, India. Electronic address: shankar.niperhyd@gov.in.
Eur J Med Chem ; 200: 112457, 2020 Aug 15.
Article en En | MEDLINE | ID: mdl-32422489
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Urea / Inhibidores de la Angiogénesis / Receptor 2 de Factores de Crecimiento Endotelial Vascular / Inhibidores de Proteínas Quinasas / Neovascularización Patológica / Antineoplásicos Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Urea / Inhibidores de la Angiogénesis / Receptor 2 de Factores de Crecimiento Endotelial Vascular / Inhibidores de Proteínas Quinasas / Neovascularización Patológica / Antineoplásicos Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article