Coincubation of sperm with epididymal extracellular vesicle preparations from chronic intermittent ethanol-treated mice is sufficient to impart anxiety-like and ethanol-induced behaviors to adult progeny.

Rompala, Gregory R; Ferguson, Carolyn; Homanics, Gregg E

Rompala, Gregory R; Ferguson, Carolyn; Homanics, Gregg E.

Rompala GR; Center for Neuroscience, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address: gregory.rompala@mssm.edu.
Ferguson C; Department of Anesthesiology and Perioperative Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address: fergusonc@anes.upmc.edu.
Homanics GE; Center for Neuroscience, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Department of Anesthesiology and Perioperative Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address: homanicsge@upmc.edu.

Alcohol ; 87: 111-120, 2020 09.

Article en En | MEDLINE | ID: mdl-32445808

Asunto(s)

Ansiedad; Etanol; Vesículas Extracelulares; Exposición Paterna; Animales; Conducta Animal; Epidídimo; Epigénesis Genética; Etanol/toxicidad; Femenino; Masculino; Ratones; Ratones Endogámicos C57BL; Espermatozoides

Palabras clave

Alcohol drinking; Epididymis; Epigenetic inheritance; Extracellular vesicles; Intergenerational; sperm

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Ansiedad / Exposición Paterna / Etanol / Vesículas Extracelulares Límite: Animals Idioma: En Año: 2020 Tipo del documento: Article

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