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Synthesis and Biological Evaluation of a Depsipeptidic Histone Deacetylase Inhibitor via a Generalizable Approach Using an Optimized Latent Thioester Solid-Phase Linker.
Zang, Xiaoyu; Peraro, Leila; Davison, Ryan T; Blum, Travis R; Vallabhaneni, Deepak; Fennell, Caitlyn E; Cramer, Stephanie L; Shah, Heli K; Wholly, Deirdre M; Fink, Elissa A; Sivak, Jacob T; Ingalls, Kathryn M; Herr, Chelsea T; Lawson, Vernon E; Burnett, Matthew R; Slade, David J; Cole, Kathryn E; Carle, Sigrid A; Miller, Justin S.
  • Zang X; Department of Chemistry, Hobart and William Smith Colleges, Geneva, New York 14456, United States.
  • Peraro L; Department of Chemistry, Hobart and William Smith Colleges, Geneva, New York 14456, United States.
  • Davison RT; Department of Chemistry, Hobart and William Smith Colleges, Geneva, New York 14456, United States.
  • Blum TR; Department of Chemistry, Hobart and William Smith Colleges, Geneva, New York 14456, United States.
  • Vallabhaneni D; Department of Biology, Hobart and William Smith Colleges, Geneva, New York 14456, United States.
  • Fennell CE; Department of Biology, Hobart and William Smith Colleges, Geneva, New York 14456, United States.
  • Cramer SL; Department of Chemistry, Hobart and William Smith Colleges, Geneva, New York 14456, United States.
  • Shah HK; Department of Chemistry, Hobart and William Smith Colleges, Geneva, New York 14456, United States.
  • Wholly DM; Department of Chemistry, Hobart and William Smith Colleges, Geneva, New York 14456, United States.
  • Fink EA; Department of Molecular Biology and Chemistry, Christopher Newport University, Newport News, Virginia 23606, United States.
  • Sivak JT; Department of Molecular Biology and Chemistry, Christopher Newport University, Newport News, Virginia 23606, United States.
  • Ingalls KM; Department of Molecular Biology and Chemistry, Christopher Newport University, Newport News, Virginia 23606, United States.
  • Herr CT; Department of Chemistry, Hobart and William Smith Colleges, Geneva, New York 14456, United States.
  • Lawson VE; Department of Chemistry, Hobart and William Smith Colleges, Geneva, New York 14456, United States.
  • Burnett MR; Department of Biology, Hobart and William Smith Colleges, Geneva, New York 14456, United States.
  • Slade DJ; Department of Chemistry, Hobart and William Smith Colleges, Geneva, New York 14456, United States.
  • Cole KE; Department of Molecular Biology and Chemistry, Christopher Newport University, Newport News, Virginia 23606, United States.
  • Carle SA; Department of Biology, Hobart and William Smith Colleges, Geneva, New York 14456, United States.
  • Miller JS; Department of Chemistry, Hobart and William Smith Colleges, Geneva, New York 14456, United States.
J Org Chem ; 85(12): 8253-8260, 2020 06 19.
Article en En | MEDLINE | ID: mdl-32452203
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Depsipéptidos / Inhibidores de Histona Desacetilasas Idioma: En Año: 2020 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Depsipéptidos / Inhibidores de Histona Desacetilasas Idioma: En Año: 2020 Tipo del documento: Article