A Bird's-Eye View of Cell Sources for Cell-Based Therapies in Blood Cancers.
Cancers (Basel)
; 12(5)2020 May 23.
Article
en En
| MEDLINE
| ID: mdl-32456165
ABSTRACT
Hematological malignancies comprise over a hundred different types of cancers and account for around 6.5% of all cancers. Despite the significant improvements in diagnosis and treatment, many of those cancers remain incurable. In recent years, cancer cell-based therapy has become a promising approach to treat those incurable hematological malignancies with striking results in different clinical trials. The most investigated, and the one that has advanced the most, is the cell-based therapy with T lymphocytes modified with chimeric antigen receptors. Those promising initial results prepared the ground to explore other cell-based therapies to treat patients with blood cancer. In this review, we want to provide an overview of the different types of cell-based therapies in blood cancer, describing them according to the cell source.
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MEDLINE
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2020
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Article