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A helper-dependent adenoviral vector rescues CFTR to wild-type functional levels in cystic fibrosis epithelial cells harbouring class I mutations.
Cao, Huibi; Ouyang, Hong; Laselva, Onofrio; Bartlett, Claire; Zhou, Zhichang Peter; Duan, Cathleen; Gunawardena, Tarini; Avolio, Julie; Bear, Christine E; Gonska, Tanja; Hu, Jim; Moraes, Theo J.
  • Cao H; Programmes in Translational Medicine, Research Institute, Hospital for Sick Children, Toronto, ON, Canada.
  • Ouyang H; Both authors contributed equally to this work.
  • Laselva O; Programmes in Translational Medicine, Research Institute, Hospital for Sick Children, Toronto, ON, Canada.
  • Bartlett C; Both authors contributed equally to this work.
  • Zhou ZP; Molecular Medicine, Research Institute, Hospital for Sick Children, Toronto, ON, Canada.
  • Duan C; Dept of Physiology, University of Toronto, Toronto, ON, Canada.
  • Gunawardena T; Programmes in Translational Medicine, Research Institute, Hospital for Sick Children, Toronto, ON, Canada.
  • Avolio J; Programmes in Translational Medicine, Research Institute, Hospital for Sick Children, Toronto, ON, Canada.
  • Bear CE; Programmes in Translational Medicine, Research Institute, Hospital for Sick Children, Toronto, ON, Canada.
  • Gonska T; Programmes in Translational Medicine, Research Institute, Hospital for Sick Children, Toronto, ON, Canada.
  • Hu J; Programmes in Translational Medicine, Research Institute, Hospital for Sick Children, Toronto, ON, Canada.
  • Moraes TJ; Molecular Medicine, Research Institute, Hospital for Sick Children, Toronto, ON, Canada.
Eur Respir J ; 56(5)2020 11.
Article en En | MEDLINE | ID: mdl-32457197
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fibrosis Quística Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fibrosis Quística Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article