Lipid droplets disrupt mechanosensing in human hepatocytes.

Chin, LiKang; Theise, Neil D; Loneker, Abigail E; Janmey, Paul A; Wells, Rebecca G

Chin, LiKang; Theise, Neil D; Loneker, Abigail E; Janmey, Paul A; Wells, Rebecca G.

Chin L; Departments of Medicine and Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania.
Theise ND; Physical Sciences in Oncology Center at Penn, University of Pennsylvania, Philadelphia, Pennsylvania.
Loneker AE; Department of Pathology, New York University School of Medicine, New York, New York.
Janmey PA; Bioengineering Graduate Group, University of Pennsylvania, Philadelphia, Pennsylvania.
Wells RG; Physical Sciences in Oncology Center at Penn, University of Pennsylvania, Philadelphia, Pennsylvania.

Am J Physiol Gastrointest Liver Physiol ; 319(1): G11-G22, 2020 07 01.

Article en En | MEDLINE | ID: mdl-32463334

Asunto(s)

Carcinoma Hepatocelular/metabolismo; Hepatocitos/metabolismo; Gotas Lipídicas/metabolismo; Neoplasias Hepáticas/metabolismo; Carcinoma Hepatocelular/patología; Núcleo Celular/metabolismo; Humanos; Metabolismo de los Lípidos/fisiología; Lípidos; Hígado/metabolismo; Neoplasias Hepáticas/patología; Enfermedad del Hígado Graso no Alcohólico/metabolismo; Enfermedad del Hígado Graso no Alcohólico/patología

Palabras clave

HCC; NAFLD; YAP; cirrhosis; lipid droplet

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Carcinoma Hepatocelular / Hepatocitos / Gotas Lipídicas / Neoplasias Hepáticas Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article

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