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Integrating untargeted metabolomics, genetically informed causal inference, and pathway enrichment to define the obesity metabolome.
Hsu, Yu-Han H; Astley, Christina M; Cole, Joanne B; Vedantam, Sailaja; Mercader, Josep M; Metspalu, Andres; Fischer, Krista; Fortney, Kristen; Morgen, Eric K; Gonzalez, Clicerio; Gonzalez, Maria E; Esko, Tonu; Hirschhorn, Joel N.
  • Hsu YH; Department of Genetics, Harvard Medical School, Boston, MA, USA.
  • Astley CM; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA.
  • Cole JB; Programs in Metabolism and Medical & Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Vedantam S; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA.
  • Mercader JM; Programs in Metabolism and Medical & Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Metspalu A; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA.
  • Fischer K; Programs in Metabolism and Medical & Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Fortney K; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Morgen EK; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA.
  • Gonzalez C; Programs in Metabolism and Medical & Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Gonzalez ME; Programs in Metabolism and Medical & Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Esko T; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Hirschhorn JN; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia.
Int J Obes (Lond) ; 44(7): 1596-1606, 2020 07.
Article en En | MEDLINE | ID: mdl-32467615

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Metaboloma / Obesidad Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Metaboloma / Obesidad Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article