Macromolecular modeling and design in Rosetta: recent methods and frameworks.
Nat Methods
; 17(7): 665-680, 2020 07.
Article
en En
| MEDLINE
| ID: mdl-32483333
ABSTRACT
The Rosetta software for macromolecular modeling, docking and design is extensively used in laboratories worldwide. During two decades of development by a community of laboratories at more than 60 institutions, Rosetta has been continuously refactored and extended. Its advantages are its performance and interoperability between broad modeling capabilities. Here we review tools developed in the last 5 years, including over 80 methods. We discuss improvements to the score function, user interfaces and usability. Rosetta is available at http//www.rosettacommons.org.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Programas Informáticos
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Proteínas
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Modelos Moleculares
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Sustancias Macromoleculares
Tipo de estudio:
Prognostic_studies
Idioma:
En
Año:
2020
Tipo del documento:
Article