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Clonal Evolution and Heterogeneity of Osimertinib Acquired Resistance Mechanisms in EGFR Mutant Lung Cancer.
Roper, Nitin; Brown, Anna-Leigh; Wei, Jun S; Pack, Svetlana; Trindade, Christopher; Kim, Chul; Restifo, Olivia; Gao, Shaojian; Sindiri, Sivasish; Mehrabadi, Farid; El Meskini, Rajaa; Ohler, Zoe Weaver; Maity, Tapan K; Venugopalan, Abhilash; Cultraro, Constance M; Akoth, Elizabeth; Padiernos, Emerson; Chen, Haobin; Kesarwala, Aparna; Smart, DeeDee K; Nilubol, Naris; Rajan, Arun; Piotrowska, Zofia; Xi, Liqiang; Raffeld, Mark; Panchenko, Anna R; Sahinalp, Cenk; Hewitt, Stephen; Hoang, Chuong D; Khan, Javed; Guha, Udayan.
  • Roper N; Thoracic and GI Malignancies Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD 20892, USA.
  • Brown AL; Present address: Developmental Therapeutics Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD 20892, USA.
  • Wei JS; National Center for Biotechnology Information, NIH, NLM, Bethesda, MD 20892, USA.
  • Pack S; Present address: UCL Institute of Neurology and MRC Centre for Neuromuscular Disease, London, UK.
  • Trindade C; Thoracic and GI Malignancies Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD 20892, USA.
  • Kim C; Laboratory of Pathology, CCR, NCI, NIH, Bethesda, MD 20892, USA.
  • Restifo O; Laboratory of Pathology, CCR, NCI, NIH, Bethesda, MD 20892, USA.
  • Gao S; Thoracic and GI Malignancies Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD 20892, USA.
  • Sindiri S; Present address: Lombardi Comprehensive Cancer Center, MedStar Georgetown University Hospital, Washington, DC 20007, USA.
  • Mehrabadi F; Present address: Lombardi Comprehensive Cancer Center, MedStar Georgetown University Hospital, Washington, DC 20007, USA.
  • El Meskini R; Thoracic and GI Malignancies Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD 20892, USA.
  • Ohler ZW; Genetics Branch, CCR, NCI, NIH, Bethesda, MD 20892, USA.
  • Maity TK; Cancer Data Science Laboratory, Center for Cancer Research, NCI, NIH, Bethesda, MD 20892, USA.
  • Venugopalan A; Center for Advanced Preclinical Research, Center for Cancer Research, NCI, NIH, Bethesda, MD 20892, USA.
  • Cultraro CM; Center for Advanced Preclinical Research, Center for Cancer Research, NCI, NIH, Bethesda, MD 20892, USA.
  • Akoth E; Thoracic and GI Malignancies Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD 20892, USA.
  • Padiernos E; Thoracic and GI Malignancies Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD 20892, USA.
  • Chen H; Thoracic and GI Malignancies Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD 20892, USA.
  • Kesarwala A; Thoracic and GI Malignancies Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD 20892, USA.
  • Smart DK; Thoracic and GI Malignancies Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD 20892, USA.
  • Nilubol N; Thoracic Surgery Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD 20892, USA.
  • Rajan A; Radiation Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD 20892, USA.
  • Piotrowska Z; Present address: Department of Radiation Oncology, Winship Cancer Institute, Emory University, Atlanta, GA 30322, USA.
  • Xi L; Radiation Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD 20892, USA.
  • Raffeld M; Surgical Oncology Program, Center for Cancer Research, NCI, NIH, Bethesda, MD 20892, USA.
  • Panchenko AR; Thoracic and GI Malignancies Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD 20892, USA.
  • Sahinalp C; Hematology and Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
  • Hewitt S; Laboratory of Pathology, CCR, NCI, NIH, Bethesda, MD 20892, USA.
  • Hoang CD; Laboratory of Pathology, CCR, NCI, NIH, Bethesda, MD 20892, USA.
  • Khan J; National Center for Biotechnology Information, NIH, NLM, Bethesda, MD 20892, USA.
  • Guha U; Present address: Department of Pathology and Molecular Medicine, School of Medicine, Queen's University, Kingston, ON, Canada and Ontario Institute of Cancer Research, Toronto, ON, Canada.
Cell Rep Med ; 1(1)2020 04 21.
Article en En | MEDLINE | ID: mdl-32483558

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Acrilamidas / Carcinoma de Pulmón de Células no Pequeñas / Resistencia a Antineoplásicos / Evolución Clonal / Compuestos de Anilina / Neoplasias Pulmonares Tipo de estudio: Prognostic_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Año: 2020 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Acrilamidas / Carcinoma de Pulmón de Células no Pequeñas / Resistencia a Antineoplásicos / Evolución Clonal / Compuestos de Anilina / Neoplasias Pulmonares Tipo de estudio: Prognostic_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Año: 2020 Tipo del documento: Article