Higher body mass index at ages 16 to 20 years is associated with increased risk of a multiple sclerosis diagnosis in subsequent adulthood among men.
Mult Scler
; 27(1): 147-150, 2021 01.
Article
en En
| MEDLINE
| ID: mdl-32507076
ABSTRACT
BACKGROUND:
Evidence for the association between body mass index (BMI) and multiple sclerosis (MS) among men remains mixed. OBJECTIVE ANDMETHODS:
Swedish military conscription and other registers identified MS after age of 20 years and BMI at ages 16-20 years (N = 744,548).RESULTS:
Each unit (kg/m2) BMI increase was associated with greater MS risk (hazard ratio and 95% confidence interval = 1.034, 1.016-1.053), independent of physical fitness (1.021, 1.001-1.042). Categorised, overweight and obesity were associated with statistically significant raised MS risk compared to normal weight, but not after adjustment for physical fitness.CONCLUSION:
MS risk rises with increasing BMI, across the entire BMI range.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Esclerosis Múltiple
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Adult
/
Humans
/
Male
Idioma:
En
Año:
2021
Tipo del documento:
Article