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2-Arylbenzo[d]oxazole Phosphinate Esters as Second-Generation Modulators of Utrophin for the Treatment of Duchenne Muscular Dystrophy.
Babbs, Arran; Berg, Adam; Chatzopoulou, Maria; Davies, Kay E; Davies, Stephen G; Edwards, Benjamin; Elsey, David J; Emer, Enrico; Guiraud, Simon; Harriman, Shawn; Lecci, Cristina; Moir, Lee; Peters, David; Robinson, Neil; Rowley, Jessica A; Russell, Angela J; Squire, Sarah E; Tinsley, Jonathon M; Wilson, Francis X; Wynne, Graham M.
  • Babbs A; MDUK Oxford Neuromuscular Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, U.K.
  • Berg A; MDUK Oxford Neuromuscular Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, U.K.
  • Chatzopoulou M; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford OX1 3TA, U.K.
  • Davies KE; MDUK Oxford Neuromuscular Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, U.K.
  • Davies SG; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford OX1 3TA, U.K.
  • Edwards B; MDUK Oxford Neuromuscular Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, U.K.
  • Elsey DJ; Summit Therapeutics plc, 136a Eastern Avenue, Milton Park, Abingdon, Oxfordshire OX14 4SB, U.K.
  • Emer E; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford OX1 3TA, U.K.
  • Guiraud S; MDUK Oxford Neuromuscular Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, U.K.
  • Harriman S; Summit Therapeutics plc, 136a Eastern Avenue, Milton Park, Abingdon, Oxfordshire OX14 4SB, U.K.
  • Lecci C; Evotec (UK) Ltd, 114 Innovation Dr, Milton Park, Milton, Abingdon OX14 4RZ, U.K.
  • Moir L; MDUK Oxford Neuromuscular Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, U.K.
  • Peters D; Summit Therapeutics plc, 136a Eastern Avenue, Milton Park, Abingdon, Oxfordshire OX14 4SB, U.K.
  • Robinson N; S.H.B. Enterprises Ltd, 55 Station Road, Beaconsfield HP19 1QL, U.K.
  • Rowley JA; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford OX1 3TA, U.K.
  • Russell AJ; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford OX1 3TA, U.K.
  • Squire SE; Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3PQ, U.K.
  • Tinsley JM; MDUK Oxford Neuromuscular Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, U.K.
  • Wilson FX; Summit Therapeutics plc, 136a Eastern Avenue, Milton Park, Abingdon, Oxfordshire OX14 4SB, U.K.
  • Wynne GM; Summit Therapeutics plc, 136a Eastern Avenue, Milton Park, Abingdon, Oxfordshire OX14 4SB, U.K.
J Med Chem ; 63(14): 7880-7891, 2020 07 23.
Article en En | MEDLINE | ID: mdl-32551645
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Benzoxazoles / Distrofia Muscular de Duchenne / Utrofina Límite: Animals Idioma: En Año: 2020 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Benzoxazoles / Distrofia Muscular de Duchenne / Utrofina Límite: Animals Idioma: En Año: 2020 Tipo del documento: Article