Non-specific protection from respiratory tract infections in cattle generated by intranasal administration of an innate immune stimulant.

Wheat, William; Chow, Lyndah; Rozo, Vanessa; Herman, Julia; Still Brooks, Kelly; Colbath, Aimee; Hunter, Randy; Dow, Steven

Wheat, William; Chow, Lyndah; Rozo, Vanessa; Herman, Julia; Still Brooks, Kelly; Colbath, Aimee; Hunter, Randy; Dow, Steven.

Wheat W; Department of Clinical Sciences, From the Center for Immune and Regenerative Medicine, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Ft. Collins, Colorado, United States of America.
Chow L; Department of Clinical Sciences, From the Center for Immune and Regenerative Medicine, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Ft. Collins, Colorado, United States of America.
Rozo V; Department of Clinical Sciences, From the Center for Immune and Regenerative Medicine, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Ft. Collins, Colorado, United States of America.
Herman J; Department of Clinical Sciences, From the Center for Immune and Regenerative Medicine, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Ft. Collins, Colorado, United States of America.
Still Brooks K; Department of Clinical Sciences, From the Center for Immune and Regenerative Medicine, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Ft. Collins, Colorado, United States of America.
Colbath A; Department of Clinical Sciences, From the Center for Immune and Regenerative Medicine, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Ft. Collins, Colorado, United States of America.
Hunter R; Hunter Cattle Company, Wheatland, Wyoming, United States of America.
Dow S; Department of Clinical Sciences, From the Center for Immune and Regenerative Medicine, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Ft. Collins, Colorado, United States of America.

PLoS One ; 15(6): e0235422, 2020.

Article en En | MEDLINE | ID: mdl-32584899

Asunto(s)

Complejo Respiratorio Bovino/patología; Inmunidad Innata/efectos de los fármacos; Fármacos del Sistema Respiratorio/farmacología; Administración Intranasal; Animales; Complejo Respiratorio Bovino/tratamiento farmacológico; Complejo Respiratorio Bovino/mortalidad; Bovinos; Antígenos de Histocompatibilidad Clase II/metabolismo; Interferón gamma/genética; Interferón gamma/metabolismo; Interleucina-6/genética; Interleucina-6/metabolismo; Leucocitos Mononucleares/citología; Leucocitos Mononucleares/metabolismo; Liposomas/química; Macrófagos/citología; Macrófagos/efectos de los fármacos; Macrófagos/inmunología; Macrófagos/metabolismo; Mannheimia haemolytica/aislamiento & purificación; Mannheimia haemolytica/patogenicidad; Nasofaringe/metabolismo; Nasofaringe/microbiología; Óxido Nítrico/metabolismo; Fagocitosis; Fármacos del Sistema Respiratorio/uso terapéutico; Tasa de Supervivencia; Receptor Toll-Like 3/agonistas; Receptor Toll-Like 9/agonistas; Regulación hacia Arriba/efectos de los fármacos

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fármacos del Sistema Respiratorio / Complejo Respiratorio Bovino / Inmunidad Innata Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2020 Tipo del documento: Article

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