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Leukoencephalopathy Associated with Severe COVID-19 Infection: Sequela of Hypoxemia?
Lang, M; Buch, K; Li, M D; Mehan, W A; Lang, A L; Leslie-Mazwi, T M; Rincon, S P.
  • Lang M; From the Departments of Radiology (M.L., K.B., M.D.L., W.A.M., Jr, S.P.R.) mlang@mgh.harvard.edu.
  • Buch K; From the Departments of Radiology (M.L., K.B., M.D.L., W.A.M., Jr, S.P.R.).
  • Li MD; From the Departments of Radiology (M.L., K.B., M.D.L., W.A.M., Jr, S.P.R.).
  • Mehan WA; From the Departments of Radiology (M.L., K.B., M.D.L., W.A.M., Jr, S.P.R.).
  • Lang AL; Anesthesia, Critical Care, and Pain Medicine (A.L.L.).
  • Leslie-Mazwi TM; Neurosurgery and Neurology (T.M.L.-M.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
  • Rincon SP; From the Departments of Radiology (M.L., K.B., M.D.L., W.A.M., Jr, S.P.R.).
AJNR Am J Neuroradiol ; 41(9): 1641-1645, 2020 09.
Article en En | MEDLINE | ID: mdl-32586959
ABSTRACT
There is increasing evidence to suggest that complications of coronavirus disease 2019 (COVID-19) infection are not only limited to the pulmonary system but can also involve the central nervous system. Here, we report 6 critically ill patients with COVID-19 infection and neuroimaging findings of leukoencephalopathy. While these findings are nonspecific, we postulate that they may be a delayed response to the profound hypoxemia the patients experienced due to the infection. No abnormal enhancement, hemorrhage, or perfusion abnormalities were noted on MR imaging. In addition, Severe Acute Respiratory Syndrome coronavirus 2 was not detected in the CSF collected from the 2 patients who underwent lumbar puncture. Recognition of COVID-19-related leukoencephalopathy is important for appropriate clinical management, disposition, and prognosis.
Asunto(s)

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neumonía Viral / Infecciones por Coronavirus / Leucoencefalopatías / Betacoronavirus / Hipoxia Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Año: 2020 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neumonía Viral / Infecciones por Coronavirus / Leucoencefalopatías / Betacoronavirus / Hipoxia Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Año: 2020 Tipo del documento: Article