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A tumor-associated splice-isoform of MAP2K7 drives dedifferentiation in MBNL1-low cancers via JNK activation.
Ray, Debleena; Yun, Yu Chye; Idris, Muhammad; Cheng, Shanshan; Boot, Arnoud; Iain, Tan Bee Huat; Rozen, Steven G; Tan, Patrick; Epstein, David M.
  • Ray D; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, 165897 Singapore, Singapore; debleena.ray@duke-nus.edu.sg david.epstein@duke-nus.edu.sg.
  • Yun YC; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, 165897 Singapore, Singapore.
  • Idris M; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, 165897 Singapore, Singapore.
  • Cheng S; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, 165897 Singapore, Singapore.
  • Boot A; Centre for Computational Biology, Duke-NUS Medical School, 165897 Singapore, Singapore.
  • Iain TBH; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, 165897 Singapore, Singapore.
  • Rozen SG; Centre for Computational Biology, Duke-NUS Medical School, 165897 Singapore, Singapore.
  • Tan P; Division of Medical Oncology, National Cancer Centre, 169610 Singapore, Singapore.
  • Epstein DM; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, 165897 Singapore, Singapore.
Proc Natl Acad Sci U S A ; 117(28): 16391-16400, 2020 07 14.
Article en En | MEDLINE | ID: mdl-32601196

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas de Unión al ARN / MAP Quinasa Quinasa 4 / MAP Quinasa Quinasa 7 / Neoplasias Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas de Unión al ARN / MAP Quinasa Quinasa 4 / MAP Quinasa Quinasa 7 / Neoplasias Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article