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Ester Prodrugs of Malonate with Enhanced Intracellular Delivery Protect Against Cardiac Ischemia-Reperfusion Injury In Vivo.
Prag, Hiran A; Pala, Laura; Kula-Alwar, Duvaraka; Mulvey, John F; Luping, Du; Beach, Timothy E; Booty, Lee M; Hall, Andrew R; Logan, Angela; Sauchanka, Volha; Caldwell, Stuart T; Robb, Ellen L; James, Andrew M; Xu, Zhelong; Saeb-Parsy, Kourosh; Hartley, Richard C; Murphy, Michael P; Krieg, Thomas.
  • Prag HA; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge, CB2 0XY, UK.
  • Pala L; Department of Medicine, University of Cambridge, Cambridge, CB2 0QQ, UK.
  • Kula-Alwar D; School of Chemistry, University of Glasgow, Glasgow, G12 8QQ, UK.
  • Mulvey JF; Department of Medicine, University of Cambridge, Cambridge, CB2 0QQ, UK.
  • Luping D; Department of Medicine, University of Cambridge, Cambridge, CB2 0QQ, UK.
  • Beach TE; Tianjin Medical University, Tianjin, 300070, China.
  • Booty LM; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, CB2 0QQ, UK.
  • Hall AR; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge, CB2 0XY, UK.
  • Logan A; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge, CB2 0XY, UK.
  • Sauchanka V; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge, CB2 0XY, UK.
  • Caldwell ST; Department of Medicine, University of Cambridge, Cambridge, CB2 0QQ, UK.
  • Robb EL; School of Chemistry, University of Glasgow, Glasgow, G12 8QQ, UK.
  • James AM; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge, CB2 0XY, UK.
  • Xu Z; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge, CB2 0XY, UK.
  • Saeb-Parsy K; Tianjin Medical University, Tianjin, 300070, China.
  • Hartley RC; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, CB2 0QQ, UK.
  • Murphy MP; School of Chemistry, University of Glasgow, Glasgow, G12 8QQ, UK.
  • Krieg T; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge, CB2 0XY, UK. mpm@mrc-mbu.cam.ac.uk.
Cardiovasc Drugs Ther ; 36(1): 1-13, 2022 02.
Article en En | MEDLINE | ID: mdl-32648168
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cardiotónicos / Daño por Reperfusión Miocárdica / Malonatos / Infarto del Miocardio Límite: Animals / Female / Humans / Male Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cardiotónicos / Daño por Reperfusión Miocárdica / Malonatos / Infarto del Miocardio Límite: Animals / Female / Humans / Male Idioma: En Año: 2022 Tipo del documento: Article