Berberine ameliorates obesity-induced chronic inflammation through suppression of ER stress and promotion of macrophage M2 polarization at least partly via downregulating lncRNA Gomafu.

Han, Yu-Bo; Tian, Miao; Wang, Xiao-Xue; Fan, De-Hui; Li, Wei-Zhong; Wu, Fan; Liu, Li

Han, Yu-Bo; Tian, Miao; Wang, Xiao-Xue; Fan, De-Hui; Li, Wei-Zhong; Wu, Fan; Liu, Li.

Han YB; The First Department of Cardiovascular, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, No. 26 Heping Road, Xiangfang District, Harbin 150040, Heilongjiang Province, PR China.
Tian M; Experimental Training Center, Heilongjiang University of Chinese Medicine, No. 24 Heping Road, Xiangfang District, Harbin 150040, Heilongjiang Province, PR China. Electronic address: tianmiao_1990@126.com.
Wang XX; Heilongjiang University of Chinese Medicine, No. 24 Heping Road, Xiangfang District, Harbin 150040, Heilongjiang Province, PR China.
Fan DH; Heilongjiang University of Chinese Medicine, No. 24 Heping Road, Xiangfang District, Harbin 150040, Heilongjiang Province, PR China.
Li WZ; Heilongjiang University of Chinese Medicine, No. 24 Heping Road, Xiangfang District, Harbin 150040, Heilongjiang Province, PR China.
Wu F; Heilongjiang University of Chinese Medicine, No. 24 Heping Road, Xiangfang District, Harbin 150040, Heilongjiang Province, PR China.
Liu L; The First Department of Cardiovascular, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, No. 26 Heping Road, Xiangfang District, Harbin 150040, Heilongjiang Province, PR China. Electronic address: liliu429@163.com.

Int Immunopharmacol ; 86: 106741, 2020 Sep.

Article en En | MEDLINE | ID: mdl-32650294

Asunto(s)

Antiinflamatorios/uso terapéutico; Berberina/uso terapéutico; Inflamación/tratamiento farmacológico; Macrófagos/inmunología; Obesidad/tratamiento farmacológico; ARN Largo no Codificante/genética; Células Th2/inmunología; Animales; Diferenciación Celular; Enfermedad Crónica; Citocinas/metabolismo; Modelos Animales de Enfermedad; Regulación hacia Abajo; Chaperón BiP del Retículo Endoplásmico; Estrés del Retículo Endoplásmico/efectos de los fármacos; Humanos; Ratones; Ratones Endogámicos C57BL; Células RAW 264.7

Palabras clave

Adipocyte; Berberine; Endoplasmic reticulum stress; Gomafu; Macrophage

Texto completo

Imprimir

XML

PubMed Links

Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Berberina / Células Th2 / ARN Largo no Codificante / Inflamación / Macrófagos / Antiinflamatorios / Obesidad Límite: Animals / Humans Idioma: En Año: 2020 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Search on Google