Perillyle alcohol and Quercetin ameliorate monocrotaline-induced pulmonary artery hypertension in rats through PARP1-mediated miR-204 down-regulation and its downstream pathway.

Rajabi, Soodeh; Najafipour, Hamid; Jafarinejad Farsangi, Saeideh; Joukar, Siyavash; Beik, Ahmad; Iranpour, Maryam; Kordestani, Zeinab

Rajabi, Soodeh; Najafipour, Hamid; Jafarinejad Farsangi, Saeideh; Joukar, Siyavash; Beik, Ahmad; Iranpour, Maryam; Kordestani, Zeinab.

Rajabi S; PhD candidate, Department of Physiology and Pharmacology, and Physiology Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences, Kerman, Iran.
Najafipour H; Cardiovascular Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Science, Kerman, Iran. najafipourh@yahoo.co.uk.
Jafarinejad Farsangi S; Department of Physiology and Pharmacology, Afzalipour Medical Faculty, Bulvd. 22 Bahman, Kerman, Iran. najafipourh@yahoo.co.uk.
Joukar S; Molecular Biology, Physiology Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Science, Kerman, Iran.
Beik A; Cardiovascular Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Science, Kerman, Iran.
Iranpour M; PhD candidate, Department of Physiology and Pharmacology, and Physiology Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences, Kerman, Iran.
Kordestani Z; Department of Pathology and Pathology and Stem Cell Research Center, Kerman University of Medical Sciences, Kerman, Iran.

BMC Complement Med Ther ; 20(1): 218, 2020 Jul 13.

Article en En | MEDLINE | ID: mdl-32660602

Asunto(s)

Hipertensión Pulmonar/tratamiento farmacológico; MicroARNs/metabolismo; Monoterpenos/farmacología; Poli(ADP-Ribosa) Polimerasa-1/metabolismo; Quercetina/farmacología; Animales; Modelos Animales de Enfermedad; Regulación hacia Abajo; Hipertrofia Ventricular Derecha/tratamiento farmacológico; Subunidad alfa del Factor 1 Inducible por Hipoxia/metabolismo; Masculino; Monocrotalina; Factores de Transcripción NFATC/metabolismo; Arteria Pulmonar; Ratas; Ratas Wistar

Palabras clave

HIF1a; NFATc2; PARP1; Perillyle alcohol; Pulmonary artery hypertension; Quercetin; miR-204

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Quercetina / Monoterpenos / MicroARNs / Poli(ADP-Ribosa) Polimerasa-1 / Hipertensión Pulmonar Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2020 Tipo del documento: Article

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