Butyrate, but not propionate, reverses maternal diet-induced neurocognitive deficits in offspring.

Yu, Linchao; Zhong, Xin; He, Yu; Shi, Yuan

Yu, Linchao; Zhong, Xin; He, Yu; Shi, Yuan.

Yu L; Department of Neonatology, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, PR China; Chongqing Key Laboratory of Child Health and Nutrition, PR C
Zhong X; Department of Neonatology, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, PR China; Chongqing Key Laboratory of Pediatrics, PR China.
He Y; Department of Neonatology, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, PR China.
Shi Y; Department of Neonatology, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, PR China; Chongqing Key Laboratory of Child Health and Nutrition, PR C

Pharmacol Res ; 160: 105082, 2020 10.

Article en En | MEDLINE | ID: mdl-32679183

Asunto(s)

Conducta Animal/efectos de los fármacos; Encéfalo/efectos de los fármacos; Butiratos/farmacología; Cognición/efectos de los fármacos; Dieta/efectos adversos; Inhibidores de Histona Desacetilasas/farmacología; Histona Desacetilasas/metabolismo; Trastornos Neurocognitivos/prevención & control; Efectos Tardíos de la Exposición Prenatal; Adulto; Fenómenos Fisiológicos Nutricionales de los Animales; Animales; Encéfalo/enzimología; Encéfalo/fisiopatología; Fibras de la Dieta/metabolismo; Modelos Animales de Enfermedad; Ácidos Grasos/sangre; Femenino; Microbioma Gastrointestinal; Humanos; Fenómenos Fisiologicos Nutricionales Maternos; Ratones Endogámicos C57BL; Trastornos Neurocognitivos/enzimología; Trastornos Neurocognitivos/etiología; Trastornos Neurocognitivos/fisiopatología; Plasticidad Neuronal/efectos de los fármacos; Estado Nutricional; Valor Nutritivo; Embarazo; Propionatos/farmacología

Palabras clave

Acetate (PubChem CID: 175); Butyrate (PubChem CID: 104775); Caproate (PubChem CID: 4398339); Cognitive function; Gut microbiota; Histone deacetylases; Isobutyrate (PubChem CID: 6590); Isovalerate (PubChem CID: 3587356); Maternal diet; Perinatal intervention; Propionate (PubChem CID: 104745); Short-chain fatty acids; Valerate (PubChem CID: 114781)

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Efectos Tardíos de la Exposición Prenatal / Conducta Animal / Encéfalo / Butiratos / Cognición / Trastornos Neurocognitivos / Dieta / Inhibidores de Histona Desacetilasas / Histona Desacetilasas Tipo de estudio: Etiology_studies Límite: Adult / Animals / Female / Humans / Pregnancy Idioma: En Año: 2020 Tipo del documento: Article

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