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CRISPR-Cas12a with an oAd Induces Precise and Cancer-Specific Genomic Reprogramming of EGFR and Efficient Tumor Regression.
Yoon, A-Rum; Jung, Bo-Kyeong; Choi, Eunyoung; Chung, Eugene; Hong, JinWoo; Kim, Jin-Soo; Koo, Taeyoung; Yun, Chae-Ok.
  • Yoon AR; Department of Bioengineering, College of Engineering, Hanyang University, Seoul 04763, Republic of Korea; Institute of Nano Science and Technology (INST), Hanyang University, Seoul 04763, Republic of Korea.
  • Jung BK; Department of Bioengineering, College of Engineering, Hanyang University, Seoul 04763, Republic of Korea.
  • Choi E; Department of Pharmaceutical Science, College of Pharmacy, Kyung Hee University, Seoul 02447, Republic of Korea.
  • Chung E; Department of Chemistry, Seoul National University, Seoul 08826, Republic of Korea.
  • Hong J; Department of Bioengineering, College of Engineering, Hanyang University, Seoul 04763, Republic of Korea; GeneMedicine Co., Ltd., Seoul 04763, Republic of Korea.
  • Kim JS; Institute for Basic Science (IBS), Daejeon 34126, Republic of Korea. Electronic address: jskim01@snu.ac.kr.
  • Koo T; Department of Pharmaceutical Science, College of Pharmacy, Kyung Hee University, Seoul 02447, Republic of Korea. Electronic address: taeyoungkoo@khu.ac.kr.
  • Yun CO; Department of Bioengineering, College of Engineering, Hanyang University, Seoul 04763, Republic of Korea; Institute of Nano Science and Technology (INST), Hanyang University, Seoul 04763, Republic of Korea; GeneMedicine Co., Ltd., Seoul 04763, Republic of Korea. Electronic address: chaeok@hanyang.ac
Mol Ther ; 28(10): 2286-2296, 2020 10 07.
Article en En | MEDLINE | ID: mdl-32682455
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: ARN Guía de Kinetoplastida / Virus Oncolíticos / Viroterapia Oncolítica / Sistemas CRISPR-Cas / Receptores ErbB / Edición Génica / Vectores Genéticos Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: ARN Guía de Kinetoplastida / Virus Oncolíticos / Viroterapia Oncolítica / Sistemas CRISPR-Cas / Receptores ErbB / Edición Génica / Vectores Genéticos Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article