A multivariate quantification of Box-Behnken design assisted method development and validation of dextromethorphan hydrobromide and desloratadine simultaneously by reverse-phase HPLC in in-house syrup formulation.

Alam, Md Irshad; Siddiqui, Aquil Ur-Rahim; Khanam, Nazia; Kamaruddin, Shaikh Jalil

Alam, Md Irshad; Siddiqui, Aquil Ur-Rahim; Khanam, Nazia; Kamaruddin, Shaikh Jalil.

Alam MI; United States Pharmacopeia-India (P) Ltd, Hyderabad, Telangana, India.
Siddiqui AU; Y B Chavan College of Pharmacy affiliated to Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, Maharashtra, India.
Khanam N; Faculty of Science and Technology, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, Maharashtra, India.
Kamaruddin SJ; Shri Bhagwan College of Pharmacy affiliated to Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, Maharashtra, India.

J Sep Sci ; 43(18): 3597-3606, 2020 Sep.

Article en En | MEDLINE | ID: mdl-32683784

Asunto(s)

Dextrometorfano/análisis; Loratadina/análogos & derivados; Cromatografía Líquida de Alta Presión/instrumentación; Composición de Medicamentos; Diseño de Equipo; Loratadina/análisis; Estructura Molecular

Palabras clave

Box-Behnken design; desloratadine; dextromethorphan hydrobromide; forced degradation; optimization techniques

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Loratadina / Dextrometorfano Idioma: En Año: 2020 Tipo del documento: Article

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Loratadina / Dextrometorfano Idioma: En Año: 2020 Tipo del documento: Article