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N-myristoyltransferase-1 is necessary for lysosomal degradation and mTORC1 activation in cancer cells.
Chen, Yu-Chuan; Navarrete, Marian S; Wang, Ying; McClintock, Natalie C; Sakurai, Reiko; Wang, Feng; Chen, Kathryn T; Chou, Tsui-Fen; Rehan, Virender K; Lee, Delphine J; Diaz, Begoña.
  • Chen YC; Division of Medical Hematology Oncology, Department of Medicine, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, 90502, USA.
  • Navarrete MS; Division of Dermatology, Department of Medicine, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, 90502, USA.
  • Wang Y; Division of Neonatology, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, 90502, USA.
  • McClintock NC; Division of Surgical Oncology, Department of Surgery, Harbor-UCLA Medical Center, Torrance, CA, 90502, USA.
  • Sakurai R; Division of Neonatology, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, 90502, USA.
  • Wang F; Division of Medical Genetics, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, 90502, USA.
  • Chen KT; Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
  • Chou TF; Division of Surgical Oncology, Department of Surgery, Harbor-UCLA Medical Center, Torrance, CA, 90502, USA.
  • Rehan VK; Division of Medical Genetics, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, 90502, USA.
  • Lee DJ; David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
  • Diaz B; Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, CA, USA.
Sci Rep ; 10(1): 11952, 2020 07 20.
Article en En | MEDLINE | ID: mdl-32686708
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Aciltransferasas / Diana Mecanicista del Complejo 1 de la Rapamicina / Lisosomas / Neoplasias Límite: Animals / Humans Idioma: En Año: 2020 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Aciltransferasas / Diana Mecanicista del Complejo 1 de la Rapamicina / Lisosomas / Neoplasias Límite: Animals / Humans Idioma: En Año: 2020 Tipo del documento: Article