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Longitudinal analyses reveal immunological misfiring in severe COVID-19.
Lucas, Carolina; Wong, Patrick; Klein, Jon; Castro, Tiago B R; Silva, Julio; Sundaram, Maria; Ellingson, Mallory K; Mao, Tianyang; Oh, Ji Eun; Israelow, Benjamin; Takahashi, Takehiro; Tokuyama, Maria; Lu, Peiwen; Venkataraman, Arvind; Park, Annsea; Mohanty, Subhasis; Wang, Haowei; Wyllie, Anne L; Vogels, Chantal B F; Earnest, Rebecca; Lapidus, Sarah; Ott, Isabel M; Moore, Adam J; Muenker, M Catherine; Fournier, John B; Campbell, Melissa; Odio, Camila D; Casanovas-Massana, Arnau; Herbst, Roy; Shaw, Albert C; Medzhitov, Ruslan; Schulz, Wade L; Grubaugh, Nathan D; Dela Cruz, Charles; Farhadian, Shelli; Ko, Albert I; Omer, Saad B; Iwasaki, Akiko.
  • Lucas C; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
  • Wong P; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
  • Klein J; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
  • Castro TBR; Laboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA.
  • Silva J; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
  • Sundaram M; Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA.
  • Ellingson MK; Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA.
  • Mao T; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
  • Oh JE; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
  • Israelow B; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
  • Takahashi T; Department of Medicine, Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT, USA.
  • Tokuyama M; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
  • Lu P; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
  • Venkataraman A; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
  • Park A; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
  • Mohanty S; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
  • Wang H; Department of Medicine, Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT, USA.
  • Wyllie AL; Department of Medicine, Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT, USA.
  • Vogels CBF; Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA.
  • Earnest R; Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA.
  • Lapidus S; Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA.
  • Ott IM; Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA.
  • Moore AJ; Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA.
  • Muenker MC; Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA.
  • Fournier JB; Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA.
  • Campbell M; Department of Medicine, Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT, USA.
  • Odio CD; Department of Medicine, Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT, USA.
  • Casanovas-Massana A; Department of Medicine, Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT, USA.
  • Shaw AC; Yale University School of Medicine, Yale Cancer Center, and Smilow Cancer Hospital, New Haven, CT, USA.
  • Medzhitov R; Department of Medicine, Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT, USA.
  • Schulz WL; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
  • Grubaugh ND; Howard Hughes Medical Institute, Chevy Chase, MD, USA.
  • Dela Cruz C; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA.
  • Farhadian S; Center for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, CT, USA.
  • Ko AI; Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA.
  • Omer SB; Department of Medicine, Section of Pulmonary and Critical Care Medicine, Yale University School of Medicine, New Haven, CT, USA.
  • Iwasaki A; Department of Medicine, Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT, USA.
Nature ; 584(7821): 463-469, 2020 08.
Article en En | MEDLINE | ID: mdl-32717743
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neumonía Viral / Citocinas / Infecciones por Coronavirus Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Año: 2020 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neumonía Viral / Citocinas / Infecciones por Coronavirus Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Año: 2020 Tipo del documento: Article