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DNA methylation repels binding of hypoxia-inducible transcription factors to maintain tumor immunotolerance.
D'Anna, Flora; Van Dyck, Laurien; Xiong, Jieyi; Zhao, Hui; Berrens, Rebecca V; Qian, Junbin; Bieniasz-Krzywiec, Pawel; Chandra, Vikas; Schoonjans, Luc; Matthews, Jason; De Smedt, Julie; Minnoye, Liesbeth; Amorim, Ricardo; Khorasanizadeh, Sepideh; Yu, Qian; Zhao, Liyun; De Borre, Marie; Savvides, Savvas N; Simon, M Celeste; Carmeliet, Peter; Reik, Wolf; Rastinejad, Fraydoon; Mazzone, Massimiliano; Thienpont, Bernard; Lambrechts, Diether.
  • D'Anna F; Center for Cancer Biology, VIB, 3000, Leuven, Belgium.
  • Van Dyck L; Laboratory of Translational Genetics, Department of Human Genetics, KU Leuven, 3000, Leuven, Belgium.
  • Xiong J; Center for Cancer Biology, VIB, 3000, Leuven, Belgium.
  • Zhao H; Laboratory of Translational Genetics, Department of Human Genetics, KU Leuven, 3000, Leuven, Belgium.
  • Berrens RV; Center for Cancer Biology, VIB, 3000, Leuven, Belgium.
  • Qian J; Laboratory of Translational Genetics, Department of Human Genetics, KU Leuven, 3000, Leuven, Belgium.
  • Bieniasz-Krzywiec P; Center for Cancer Biology, VIB, 3000, Leuven, Belgium.
  • Chandra V; Laboratory of Translational Genetics, Department of Human Genetics, KU Leuven, 3000, Leuven, Belgium.
  • Schoonjans L; Epigenetics Programme, Babraham Institute, Cambridge, CB22 3AT, UK.
  • Matthews J; The Old Schools, University of Cambridge, Trinity Lane Cambridge, CB2 1TN, UK.
  • De Smedt J; Center for Cancer Biology, VIB, 3000, Leuven, Belgium.
  • Minnoye L; Laboratory of Translational Genetics, Department of Human Genetics, KU Leuven, 3000, Leuven, Belgium.
  • Amorim R; Center for Cancer Biology, VIB, 3000, Leuven, Belgium.
  • Khorasanizadeh S; Laboratory of Tumor Inflammation and Angiogenesis, Department of Oncology, KU Leuven, 3000, Leuven, Belgium.
  • Yu Q; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Zhao L; Center for Cancer Biology, VIB, 3000, Leuven, Belgium.
  • De Borre M; State Key Laboratory of Ophthalmology, Zhongsan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, China.
  • Savvides SN; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology, Leuven Cancer Institute, KU Leuven, 3000, Leuven, Belgium.
  • Simon MC; Institute of Basic Medical Sciences, University of Oslo, 0372, Oslo, Norway.
  • Carmeliet P; Laboratory of Dermatology, Department of Oncology, KU Leuven, 3000, Leuven, Belgium.
  • Reik W; Center for Cancer Biology, VIB, 3000, Leuven, Belgium.
  • Rastinejad F; Laboratory of Translational Genetics, Department of Human Genetics, KU Leuven, 3000, Leuven, Belgium.
  • Mazzone M; Center for Cancer Biology, VIB, 3000, Leuven, Belgium.
  • Thienpont B; Laboratory of Tumor Inflammation and Angiogenesis, Department of Oncology, KU Leuven, 3000, Leuven, Belgium.
  • Lambrechts D; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Genome Biol ; 21(1): 182, 2020 07 27.
Article en En | MEDLINE | ID: mdl-32718321
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Escape del Tumor / Metilación de ADN / Factores de Transcripción con Motivo Hélice-Asa-Hélice Básico / Factor 1 Inducible por Hipoxia / Hipoxia Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Escape del Tumor / Metilación de ADN / Factores de Transcripción con Motivo Hélice-Asa-Hélice Básico / Factor 1 Inducible por Hipoxia / Hipoxia Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article