Your browser doesn't support javascript.
loading
The utility of a differentiated preclinical liver model, HepaRG cells, in investigating delayed toxicity via inhibition of mitochondrial-replication induced by fialuridine.
Jolly, Carol E; Douglas, Oisin; Kamalian, Laleh; Jenkins, Rosalind E; Beckett, Alison J; Penman, Sophie L; Williams, Dominic P; Monshouwer, Mario; Simic, Damir; Snoeys, Jan; Park, B Kevin; Chadwick, Amy E.
  • Jolly CE; MRC Centre for Drug Safety Science, The Department of Pharmacology and Therapeutics, The University of Liverpool, Ashton Street, Liverpool L69 3GE, UK.
  • Douglas O; MRC Centre for Drug Safety Science, The Department of Pharmacology and Therapeutics, The University of Liverpool, Ashton Street, Liverpool L69 3GE, UK.
  • Kamalian L; MRC Centre for Drug Safety Science, The Department of Pharmacology and Therapeutics, The University of Liverpool, Ashton Street, Liverpool L69 3GE, UK.
  • Jenkins RE; MRC Centre for Drug Safety Science, The Department of Pharmacology and Therapeutics, The University of Liverpool, Ashton Street, Liverpool L69 3GE, UK.
  • Beckett AJ; Cellular and Molecular Physiology, The University of Liverpool, Crown Street, Liverpool L69 3BX, UK.
  • Penman SL; MRC Centre for Drug Safety Science, The Department of Pharmacology and Therapeutics, The University of Liverpool, Ashton Street, Liverpool L69 3GE, UK.
  • Williams DP; Innovative Medicines and Early Development, Drug Safety and Metabolism, Translational Safety, AstraZeneca, Cambridge, UK.
  • Monshouwer M; Pharmacokinetics Dynamics and Metabolism, Janssen Research and Development, Beerse, Belgium.
  • Simic D; Mechanistic and Investigative Toxicology, Janssen Research and Development, Spring House, PA, USA.
  • Snoeys J; Pharmacokinetics Dynamics and Metabolism, Janssen Research and Development, Beerse, Belgium.
  • Park BK; MRC Centre for Drug Safety Science, The Department of Pharmacology and Therapeutics, The University of Liverpool, Ashton Street, Liverpool L69 3GE, UK.
  • Chadwick AE; MRC Centre for Drug Safety Science, The Department of Pharmacology and Therapeutics, The University of Liverpool, Ashton Street, Liverpool L69 3GE, UK. Electronic address: Amy.Chadwick@liverpool.ac.uk.
Toxicol Appl Pharmacol ; 403: 115163, 2020 09 15.
Article en En | MEDLINE | ID: mdl-32730777
Asunto(s)
Palabras clave
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Antivirales / Arabinofuranosil Uracilo / Hepatocitos / Mitocondrias Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Antivirales / Arabinofuranosil Uracilo / Hepatocitos / Mitocondrias Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article