Blood Pressure Dynamics After Pubertal Suppression with Gonadotropin-Releasing Hormone Analogs Followed by Testosterone Treatment in Transgender Male Adolescents: A Pilot Study.
LGBT Health
; 7(6): 340-344, 2020.
Article
en En
| MEDLINE
| ID: mdl-32735503
ABSTRACT
Purpose:
We analyzed blood pressure (BP) changes in transgender male adolescents treated with gonadotropin-releasing hormone analogs (GnRHa) and after adding testosterone treatment.Methods:
This was a retrospective pilot study. Outcome measures included systolic BP (SBP) and diastolic BP (DBP) before and after GnRHa initiation and after adding testosterone.Results:
Fifteen transgender male adolescents received GnRHa. DBP percentiles increased significantly after GnRHa treatment (from 55.9% ± 26.4 to 73.6% ± 9.4, p = 0.019). BP levels did not meet criteria for hypertension. DBP percentiles were restored after adding testosterone.Conclusion:
GnRHa may increase DBP in transgender male adolescents, and testosterone treatment may restore it. Further larger studies are indicated.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Testosterona
/
Presión Sanguínea
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Hormona Liberadora de Gonadotropina
/
Personas Transgénero
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Disforia de Género
Tipo de estudio:
Observational_studies
Límite:
Adolescent
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Female
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Humans
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Male
Idioma:
En
Año:
2020
Tipo del documento:
Article