Secretion of the epithelial sodium channel chaperone PCSK9 from the cortical collecting duct links sodium retention with hypercholesterolemia in nephrotic syndrome.

Molina-Jijon, Eduardo; Gambut, Stéphanie; Macé, Camille; Avila-Casado, Carmen; Clement, Lionel C

Molina-Jijon, Eduardo; Gambut, Stéphanie; Macé, Camille; Avila-Casado, Carmen; Clement, Lionel C.

Molina-Jijon E; Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, USA.
Gambut S; Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, USA.
Macé C; Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, USA.
Avila-Casado C; Department of Pathology, Toronto General Hospital, University of Toronto, Toronto, Canada.
Clement LC; Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, USA. Electronic address: lionel_clement@rush.edu.

Kidney Int ; 98(6): 1449-1460, 2020 12.

Article en En | MEDLINE | ID: mdl-32750454

Asunto(s)

Hipercolesterolemia; Síndrome Nefrótico; Animales; Acuaporina 2; Canales Epiteliales de Sodio/genética; Humanos; Hipercolesterolemia/genética; Masculino; Ratones; Ratones Endogámicos C57BL; Proproteína Convertasa 9/genética; Ratas; Sodio/metabolismo

Palabras clave

PCSK9; cortical collecting duct; hypercholesterolemia; nephrotic syndrome

Texto completo

Imprimir

XML

PubMed Links

Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Hipercolesterolemia / Síndrome Nefrótico Límite: Animals / Humans / Male Idioma: En Año: 2020 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Search on Google