In Vivo Estimates of Liver Metabolic Flux Assessed by <sup>13</sup>C-Propionate and <sup>13</sup>C-Lactate Are Impacted by Tracer Recycling and Equilibrium Assumptions.

Hasenour, Clinton M; Rahim, Mohsin; Young, Jamey D

In Vivo Estimates of Liver Metabolic Flux Assessed by ¹³C-Propionate and ¹³C-Lactate Are Impacted by Tracer Recycling and Equilibrium Assumptions.

Hasenour, Clinton M; Rahim, Mohsin; Young, Jamey D.

Hasenour CM; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN 37235, USA.
Rahim M; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN 37235, USA.
Young JD; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN 37235, USA; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN 37235, USA. Electronic address: j.d.young@vanderbilt.edu.

Cell Rep ; 32(5): 107986, 2020 08 04.

Article en En | MEDLINE | ID: mdl-32755580

Asunto(s)

Isótopos de Carbono/metabolismo; Marcaje Isotópico; Ácido Láctico/metabolismo; Hígado/metabolismo; Análisis de Flujos Metabólicos; Propionatos/metabolismo; Animales; Ciclo del Ácido Cítrico; Fumaratos/metabolismo; Hidrógeno/metabolismo; Masculino; Ratones Endogámicos C57BL; Modelos Biológicos; Ácido Oxaloacético/metabolismo; Ácido Pirúvico/metabolismo

Palabras clave

Cori cycling; anaplerosis; citric acid cycle; flux regression; gluconeogenesis; liver metabolism; metabolic flux analysis; pyruvate cycling; pyruvate kinase; stable isotope

Texto completo

Imprimir

XML

PubMed Links

Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Propionatos / Isótopos de Carbono / Ácido Láctico / Análisis de Flujos Metabólicos / Marcaje Isotópico / Hígado Límite: Animals Idioma: En Año: 2020 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Search on Google