Phosphoproteomic analysis identifies phospho-Threonine-17 site of phospholamban important in low molecular weight isoform of fibroblast growth factor 2-induced protection against post-ischemic cardiac dysfunction.

Manning, Janet R; Wijeratne, Aruna B; Oloizia, Brian B; Zhang, Yu; Greis, Kenneth D; Schultz, Jo El J

Manning, Janet R; Wijeratne, Aruna B; Oloizia, Brian B; Zhang, Yu; Greis, Kenneth D; Schultz, Jo El J.

Manning JR; Department of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, OH 45267, United States of America.
Wijeratne AB; Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH 45267, United States of America.
Oloizia BB; Department of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, OH 45267, United States of America.
Zhang Y; Department of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, OH 45267, United States of America.
Greis KD; Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH 45267, United States of America.
Schultz JEJ; Department of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, OH 45267, United States of America. Electronic address: schuljo@ucmail.uc.edu.

J Mol Cell Cardiol ; 148: 1-14, 2020 11.

Article en En | MEDLINE | ID: mdl-32853649

Asunto(s)

Proteínas de Unión al Calcio/metabolismo; Cardiotónicos/farmacología; Factor 2 de Crecimiento de Fibroblastos/metabolismo; Isquemia Miocárdica/prevención & control; Isquemia Miocárdica/fisiopatología; Fosfoproteínas/metabolismo; Fosfotreonina/metabolismo; Proteómica; Animales; Proteína Quinasa Tipo 2 Dependiente de Calcio Calmodulina/metabolismo; Ratones; Modelos Biológicos; Peso Molecular; Fosforilación; Proteína Quinasa C-alfa/metabolismo; Retículo Sarcoplasmático/metabolismo

Palabras clave

Fibroblast growth factor; Ischemia-reperfusion injury; Mass spectrometry; Phospholamban phosphorylation; Proteomics and genomics

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fosfoproteínas / Fosfotreonina / Proteínas de Unión al Calcio / Cardiotónicos / Factor 2 de Crecimiento de Fibroblastos / Isquemia Miocárdica / Proteómica Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2020 Tipo del documento: Article

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