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Cross-Module Enoylreduction in the Azalomycin F Polyketide Synthase.
Zhai, Guifa; Wang, Wenyan; Xu, Wei; Sun, Guo; Hu, Chaoqun; Wu, Xiangming; Cong, Zisong; Deng, Liang; Shi, Yanrong; Leadlay, Peter F; Song, Heng; Hong, Kui; Deng, Zixin; Sun, Yuhui.
  • Zhai G; Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Wuhan University), Ministry of Education, and School of Pharmaceutical Sciences, Wuhan University, No. 185 East Lake Road, Wuhan, 430071, P. R. China.
  • Wang W; College of Chemistry and Molecular Sciences, Wuhan University, No. 299 Bayi Road, Wuhan, 430072, P. R. China.
  • Xu W; Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Wuhan University), Ministry of Education, and School of Pharmaceutical Sciences, Wuhan University, No. 185 East Lake Road, Wuhan, 430071, P. R. China.
  • Sun G; Current address: Singapore Institute of Food and Biotechnology Innovation, Agency for Science, Technology, and Research (A*STAR), Singapore, Singapore.
  • Hu C; Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Wuhan University), Ministry of Education, and School of Pharmaceutical Sciences, Wuhan University, No. 185 East Lake Road, Wuhan, 430071, P. R. China.
  • Wu X; Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Wuhan University), Ministry of Education, and School of Pharmaceutical Sciences, Wuhan University, No. 185 East Lake Road, Wuhan, 430071, P. R. China.
  • Cong Z; Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Wuhan University), Ministry of Education, and School of Pharmaceutical Sciences, Wuhan University, No. 185 East Lake Road, Wuhan, 430071, P. R. China.
  • Deng L; College of Chemistry and Molecular Sciences, Wuhan University, No. 299 Bayi Road, Wuhan, 430072, P. R. China.
  • Shi Y; Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Wuhan University), Ministry of Education, and School of Pharmaceutical Sciences, Wuhan University, No. 185 East Lake Road, Wuhan, 430071, P. R. China.
  • Leadlay PF; Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Wuhan University), Ministry of Education, and School of Pharmaceutical Sciences, Wuhan University, No. 185 East Lake Road, Wuhan, 430071, P. R. China.
  • Song H; Department of Biochemistry, University of Cambridge, No. 80 Tennis Court Road, Cambridge, CB2 1GA, UK.
  • Hong K; College of Chemistry and Molecular Sciences, Wuhan University, No. 299 Bayi Road, Wuhan, 430072, P. R. China.
  • Deng Z; Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Wuhan University), Ministry of Education, and School of Pharmaceutical Sciences, Wuhan University, No. 185 East Lake Road, Wuhan, 430071, P. R. China.
  • Sun Y; Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Wuhan University), Ministry of Education, and School of Pharmaceutical Sciences, Wuhan University, No. 185 East Lake Road, Wuhan, 430071, P. R. China.
Angew Chem Int Ed Engl ; 59(50): 22738-22742, 2020 12 07.
Article en En | MEDLINE | ID: mdl-32865309
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Macrólidos / Sintasas Poliquetidas Idioma: En Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Macrólidos / Sintasas Poliquetidas Idioma: En Año: 2020 Tipo del documento: Article