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Safety and immunogenicity of co-administered hookworm vaccine candidates Na-GST-1 and Na-APR-1 in Gabonese adults: a randomised, controlled, double-blind, phase 1 dose-escalation trial.
Adegnika, Ayola A; de Vries, Sophia G; Zinsou, Frejus J; Honkepehedji, Yabo J; Dejon Agobé, Jean-Claude; Vodonou, Kafui G; Bikangui, Rodrigue; Bouyoukou Hounkpatin, Aurore; Bache, Emmanuel B; Massinga Loembe, Marguerite; van Leeuwen, Remko; Molemans, Marjan; Kremsner, Peter G; Yazdanbakhsh, Maria; Hotez, Peter J; Bottazzi, Maria Elena; Li, Guangzhao; Bethony, Jeffrey M; Diemert, David J; Grobusch, Martin P.
  • Adegnika AA; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon; Institut für Tropenmedizin, Universität Tübingen, Tübingen, Germany; Department of Parasitology, Leiden University Medical Center, Leiden, Netherlands; German Center for Infection Research, Tübingen, Germany.
  • de Vries SG; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon; Center of Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Division of Internal Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands.
  • Zinsou FJ; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon; Institut für Tropenmedizin, Universität Tübingen, Tübingen, Germany.
  • Honkepehedji YJ; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon; Institut für Tropenmedizin, Universität Tübingen, Tübingen, Germany.
  • Dejon Agobé JC; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon; Institut für Tropenmedizin, Universität Tübingen, Tübingen, Germany; Center of Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Division of Internal Medicine, Amsterdam University Medical Centers, University of A
  • Vodonou KG; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.
  • Bikangui R; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.
  • Bouyoukou Hounkpatin A; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon; Institut für Tropenmedizin, Universität Tübingen, Tübingen, Germany.
  • Bache EB; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon; Institut für Tropenmedizin, Universität Tübingen, Tübingen, Germany; Center of Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Division of Internal Medicine, Amsterdam University Medical Centers, University of A
  • Massinga Loembe M; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon; Institut für Tropenmedizin, Universität Tübingen, Tübingen, Germany.
  • van Leeuwen R; Amsterdam Institute for Global Development, Amsterdam, Netherlands.
  • Molemans M; Amsterdam Institute for Global Development, Amsterdam, Netherlands.
  • Kremsner PG; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon; Institut für Tropenmedizin, Universität Tübingen, Tübingen, Germany; German Center for Infection Research, Tübingen, Germany.
  • Yazdanbakhsh M; Department of Parasitology, Leiden University Medical Center, Leiden, Netherlands.
  • Hotez PJ; Texas Children's Hospital Center for Vaccine Development, Departments of Pediatrics and Molecular Virology and Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA.
  • Bottazzi ME; Texas Children's Hospital Center for Vaccine Development, Departments of Pediatrics and Molecular Virology and Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA.
  • Li G; Department of Microbiology, Immunology and Tropical Medicine, School of Medicine and Health Sciences, The George Washington University, Washington, DC, USA.
  • Bethony JM; Department of Microbiology, Immunology and Tropical Medicine, School of Medicine and Health Sciences, The George Washington University, Washington, DC, USA.
  • Diemert DJ; Department of Microbiology, Immunology and Tropical Medicine, School of Medicine and Health Sciences, The George Washington University, Washington, DC, USA. Electronic address: ddiemert@gwu.edu.
  • Grobusch MP; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon; Institut für Tropenmedizin, Universität Tübingen, Tübingen, Germany; Center of Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Division of Internal Medicine, Amsterdam University Medical Centers, University of A
Lancet Infect Dis ; 21(2): 275-285, 2021 02.
Article en En | MEDLINE | ID: mdl-32926834
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Vacunas / Necator americanus / Infecciones por Uncinaria Tipo de estudio: Clinical_trials / Guideline / Prognostic_studies Límite: Adult / Animals / Female / Humans / Male País como asunto: Africa Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Vacunas / Necator americanus / Infecciones por Uncinaria Tipo de estudio: Clinical_trials / Guideline / Prognostic_studies Límite: Adult / Animals / Female / Humans / Male País como asunto: Africa Idioma: En Año: 2021 Tipo del documento: Article